Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G1B | P04054 | 1/20 | 0.39 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 4/20 | 0.34 |
| ▸ | OPRD1 | P41143 | 4/20 | 0.34 |
| ▸ | OPRK1 | P41145 | 4/20 | 0.34 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3409861 | 0.94 | PLA2G1B (0.39) | PLA2G1BPLA2G2AALDH1A1SIGMAR1OPRM1 | |
| SCHEMBL20076527 | 0.88 | CYP1A2 (0.39) | PLA2G1BPLA2G2AALDH1A1SIGMAR1OPRM1 | |
| SCHEMBL13440530 | 0.86 | PLA2G1B (0.40) | PLA2G1BPLA2G2AALDH1A1OPRM1OPRD1 | |
| SCHEMBL472095 | 0.83 | ALDH1A1 (0.43) | ALDH1A1OPRM1OPRD1OPRK1CYP1A2 | |
| SCHEMBL441038 | 0.82 | SIGMAR1 (0.43) | PLA2G1BPLA2G2ASIGMAR1OPRM1SLC22A1 | |
| SCHEMBL23192258 | 0.82 | PLA2G1B (0.33) | PLA2G1BPLA2G2AALDH1A1OPRM1OPRD1 | |
| SCHEMBL18689513 | 0.82 | PLA2G1B (0.33) | PLA2G1BPLA2G2AALDH1A1OPRM1OPRD1 | |
| SCHEMBL12225618 | 0.82 | ALDH1A1 (0.37) | PLA2G1BPLA2G2AALDH1A1SIGMAR1 | |
| SCHEMBL13143549 | 0.82 | CYP1A2 (0.47) | PLA2G1BPLA2G2AALDH1A1SIGMAR1OPRM1 | |
| SCHEMBL441443 | 0.80 | SIGMAR1 (0.52) | PLA2G1BPLA2G2ASIGMAR1SLC22A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 228 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024147972-A2 | DNA POLYMERASE THETA INHIBITORS CONTAINING NON-SATURATED 5-MEMBERED HETEROCYCLIC RINGS AND USE THEREOF | THOMAS JEFFERSON UNIVERSITY (US) | 2024-07-11 | — | — | WO | disclosed |
| US-12024484-B2 | Lipid formulations for gene editing | VERVE THERAPEUTICS, INC. (US) | 2024-07-02 | — | — | US | disclosed |
| US-12024484-B2 | Lipid formulations for gene editing | VERVE THERAPEUTICS, INC. (US) | 2024-07-02 | — | — | US | disclosed |
| US-20240208967-A1 | Pyrimidine or Pyridine Compounds, Preparation Method Therefor and Pharmaceutical Uses Thereof | INVENTISBIO CO LTD (CN) | 2024-06-27 | — | — | US | disclosed |
| WO-2024103494-A1 | LOCALLY ACTING ANDROGEN RECEPTOR ANTAGONIST AND USE THEREOF | 南京思聚生物医药有限公司 | 2024-05-23 | — | — | WO | disclosed |
| US-11813260-B1 | Benzamide compounds | RECURIUM IP HOLDINGS, LLC (US) | 2023-11-14 | — | — | US | disclosed |
| US-11813259-B2 | Benzamide compounds | RECURIUM IP HOLDINGS, LLC (US) | 2023-11-14 | — | — | US | disclosed |
| US-11813259-B2 | Benzamide compounds | RECURIUM IP HOLDINGS, LLC (US) | 2023-11-14 | — | — | US | disclosed |
| US-11787781-B2 | Inhibiting ataxia telangiectasia and RAD3-related protein (ATR) | CELATOR PHARMACEUTICALS, INC. (US) | 2023-10-17 | — | — | US | disclosed |
| US-20230322785-A1 | ADENOSINE A2A AND A2B RECEPTOR DUAL ANTAGONISTS FOR IMMUNO-ONCOLOGY | MERCK SHARP & DOHME LLC (US) | 2023-10-12 | — | — | US | disclosed |
| EP-1250363-A2 | CHEMICAL COMPOUND, METHOD FOR THE PRODUCTION THEREOF AND ITS USE IN CATALYST SYSTEMS FOR PRODUCING POLYOLEFINS | Basell Polyolefine GmbH (DE) | 2002-10-23 | — | — | EP | disclosed |
| US-20020099214-A1 | Compounds useful in therapy | PFIZER INC. (US) | 2002-07-25 | — | — | US | disclosed |
| WO-2001090112-A1 | CHEMICAL PRODUCTS SUITED FOR USE AS CO-CATALYSTS, METHOD FOR THE PREPARATION THEREOF AND THEIR USE IN CATALYST SYSTEMS FOR PRODUCING POLYOLEFINS | BASELL POLYOLEFINE GMBH (DE) | 2001-11-29 | — | — | WO | disclosed |
| EP-0838508-B1 | Aqueous ink composition for use in an ink-jet printer | SEIKO EPSON CORP (JP) | 2001-08-29 | — | — | EP | disclosed |
| WO-2001047635-A2 | SUPPORTED CATALYST SYSTEM CONTAINING A METALLOCENE, A LEWIS BASE AND AN ELEMENTALLY ORGANIC COMPOUND OF MAIN GROUP III AND THE USE THEREOF | BASELL POLYPROPYLEN GMBH (DE) | 2001-07-05 | — | — | WO | disclosed |
| WO-2001048035-A2 | CHEMICAL COMPOUND, METHOD FOR THE PRODUCTION THEREOF AND ITS USE IN CATALYST SYSTEMS FOR PRODUCING POLYOLEFINS | BASELL POLYOLEFINE GMBH (DE) | 2001-07-05 | — | — | WO | disclosed |
| EP-1072594-A2 | 4-arylpiperidine derivatives for the treatment of pruritus | PFIZER INC. (US) | 2001-01-31 | — | — | EP | disclosed |
| EP-1072596-A2 | 4-arylpiperidine derivatives for the treatment of pruritus | PFIZER INC. (US) | 2001-01-31 | — | — | EP | disclosed |
| US-5871572-A | COLORANT, WATER, A WATER-SOLUBLE ORGANIC SOLVENT, AND PECTIC ACID | SEIKO EPSON CORPORATION (JP) | 1999-02-16 | — | — | US | disclosed |
| EP-0838508-A2 | Aqueous ink composition for use in an ink-jet printer | SEIKO EPSON CORPORATION (JP) | 1998-04-29 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12024484-B2 | Lipid formulations for gene editing | LIPA, LIPC, ABHD16A | PLA2G1B 125/4885PLA2G2A 64/4885ALDH1A1 2870/4885 |
| US-20020099214-A1 | Compounds useful in therapy | HRH2, ITCH, HRH4 | PLA2G1B 1972/4885PLA2G2A 2600/4885ALDH1A1 306/4885 |
| US-11813259-B2 | Benzamide compounds | MKI67, TMBIM6, HDAC1 | PLA2G1B 4849/4885PLA2G2A 4875/4885ALDH1A1 81/4885 |
| US-11813260-B1 | Benzamide compounds | MKI67, TMBIM6, HDAC1 | PLA2G1B 4849/4885PLA2G2A 4875/4885ALDH1A1 81/4885 |
| US-20240208967-A1 | Pyrimidine or Pyridine Compounds, Preparation Method Therefor and Pharmaceutical Uses Thereof | EGFR, WEE1, DPYD | PLA2G1B 2315/4885PLA2G2A 3287/4885ALDH1A1 1173/4885 |
| US-20230322785-A1 | ADENOSINE A2A AND A2B RECEPTOR DUAL ANTAGONISTS FOR IMMUNO-ONCOLOGY | ADORA2A, ADORA2B, ADORA1 | PLA2G1B 57/4885PLA2G2A 75/4885ALDH1A1 638/4885 |
| US-11787781-B2 | Inhibiting ataxia telangiectasia and RAD3-related protein (ATR) | ATR, CHEK2, CHEK1 | PLA2G1B 2515/4885PLA2G2A 2314/4885ALDH1A1 4550/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.