Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX3 | P56373 | 2/20 | 0.31 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.31 |
| ▸ | KDR | P35968 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20439493 | 0.89 | PTGS2 (0.37) | P2RX3PDGFRAKDRHTTKMT2A | |
| SCHEMBL23072688 | 0.86 | KDR (0.35) | P2RX3PDGFRAKDR | |
| SCHEMBL20437178 | 0.83 | PKM (0.34) | P2RX3PDGFRAKDRKMT2AL3MBTL1 | |
| SCHEMBL23072613 | 0.82 | LMNA (0.35) | P2RX3PDGFRAKDRKMT2AL3MBTL1 | |
| SCHEMBL23072622 | 0.82 | — | — | |
| SCHEMBL20422592 | 0.74 | PPARG (0.36) | P2RX3KMT2AL3MBTL1 | |
| SCHEMBL20422591 | 0.74 | PPARG (0.36) | P2RX3KMT2AL3MBTL1 | |
| SCHEMBL20422482 | 0.74 | L3MBTL1 (0.38) | P2RX3PDGFRAKDRKMT2AL3MBTL1 | |
| SCHEMBL20437176 | 0.71 | PTGS2 (0.39) | P2RX3PDGFRAKDRL3MBTL1 | |
| SCHEMBL23072670 | 0.68 | PDGFRA (0.35) | PDGFRAKDRHTTKMT2AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3573987-B1 | TYROSINE AMIDE DERIVATIVES AS RHO- KINASE INHIBITORS | CHIESI FARM SPA (IT) | 2021-03-10 | — | — | EP | disclosed |
| WO-2018138293-A1 | TYROSINE AMIDE DERIVATIVES AS RHO- KINASE INHIBITORS | CHIESI FARMACEUTICI S.P.A. (IT) | 2018-08-02 | — | — | WO | disclosed |