SCHEMBL204489

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL16709304	0.88	ADORA3 (0.47)	ADORA3ADORA2AADORA1CSNK1DPTPRC
	SCHEMBL2756208	0.76	CNR2 (0.43)	ALDH1A1SMN1; SMN2RAB9AMEN1KMT2A
	SCHEMBL16632075	0.74	ALDH1A1 (0.60)	PTPRCPTPN1ALDH1A1MEN1KMT2A
	SCHEMBL18328054	0.73	CSNK1D (0.47)	ADORA3ADORA2AADORA1CSNK1DPTPRC
	SCHEMBL16709314	0.73	CSNK1D (0.45)	ADORA3ADORA2AADORA1CSNK1DPTPRC
	SCHEMBL8482565	0.73	KDM4E (0.73)	ADORA3ADORA2AADORA1CSNK1DPTPRC
	SCHEMBL24978697	0.72	CSNK1D (0.49)	ADORA3ADORA2AADORA1CSNK1DPTPRC
	SCHEMBL21685481	0.72	TDP1 (0.50)	ADORA3ADORA2AADORA1CSNK1DPTPRC
	SCHEMBL839348	0.72	NAMPT (0.66)	ADORA3ADORA2AADORA1CSNK1DPTPRC
	SCHEMBL2349758	0.72	NAMPT (0.70)	ADORA3ADORA2AADORA1CSNK1DPTPRC

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.