SCHEMBL2045167

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2045166	1.00	APP (0.46)	APPMAOBAKR1B1PTGS2AKR1B10
	SCHEMBL31124842	0.89	CYP3A4 (0.50)	PTGS2CNR2KDM4EALDH1A1LMNA
	SCHEMBL891764	0.87	APP (0.59)	APPMAOBAKR1B1PTGS2AKR1B10
	SCHEMBL1397053	0.87	APP (0.59)	APPMAOBAKR1B1PTGS2AKR1B10
	SCHEMBL555296	0.87	APP (0.59)	APPMAOBAKR1B1PTGS2AKR1B10
	Hydrochloric Acid SCHEMBL10484291	0.84	APP (0.56)	APPMAOBAKR1B1PTGS2AKR1B10
	SCHEMBL17084645	0.81	KDM4E (0.43)	MAOBCNR2KDM4EALDH1A1LMNA
	SCHEMBL18199531	0.80	PTGES (0.53)	APPMAOBAKR1B1PTGS2CNR2
	Phenol SCHEMBL3488360	0.78	APP (0.50)	APPMAOBAKR1B1PTGS2AKR1B10
	4-Vinylphenol SCHEMBL17478290	0.77	APP (0.48)	APPMAOBAKR1B1PTGS2CNR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 149 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.