SCHEMBL2045808

SCHEMBL2045808

Oc1ccc(C2(c3ccc(O)cc3)CCC(c3ccccc3)CC2)cc1

nearest known ligand 0.52

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
ESR2 Q92731 13/20 0.52
ESR1 P03372 6/20 0.52
DEGS1 O15121 1/20 0.41
HSD11B1 P28845 1/20 0.41
SLC18A3 Q16572 1/20 0.41
SIGMAR1 Q99720 1/20 0.41
CYP3A4 P08684 2/20 0.41
CYP2C9 P11712 2/20 0.41
TRPA1 O75762 1/20 0.40
CYP2D6 P10635 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2951103 0.91 ESR2 (0.61) ESR2ESR1CYP3A4CYP2C9CYP2D6
SCHEMBL13379632 0.90 ESR2 (0.50) ESR2ESR1CYP3A4CYP2C9CYP2D6
SCHEMBL2951451 0.84 ESR2 (0.60) ESR2ESR1CYP3A4CYP2C9CYP2D6
SCHEMBL7521407 0.84 ESR2 (0.54) ESR2ESR1DEGS1HSD11B1SLC18A3
SCHEMBL9074317 0.83 ESR2 (0.57) ESR2ESR1CYP3A4CYP2C9CYP2D6
SCHEMBL2043249 0.80 TRPA1 (0.54) ESR2ESR1HSD11B1CYP3A4CYP2C9
SCHEMBL2953804 0.80 ESR2 (0.54) ESR2ESR1CYP3A4CYP2C9CYP2D6
SCHEMBL157149 0.80 ESR2 (0.53) ESR2ESR1CYP2C9CYP2D6
SCHEMBL3809814 0.80 ESR2 (0.46) ESR2ESR1CYP3A4CYP2C9CYP2D6
SCHEMBL9074414 0.79 ESR2 (0.53) ESR2ESR1CYP3A4CYP2C9CYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 183 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3489303-B1 POLYCARBONATE RESIN COMPOSITION MITSUBISHI ENG PLASTICS CORP (JP) 2026-05-27 EP disclosed
WO-2026100594-A1 POLYCARBONATE RESIN COMPOSITION 三菱エンジニアリングプラスチックス株式会社 2026-05-15 WO disclosed
WO-2026100197-A1 POLYCARBONATE RESIN COMPOSITION 三菱エンジニアリングプラスチックス株式会社 2026-05-15 WO disclosed
US-20260125537-A1 POLYCARBONATE RESIN COMPOSITION MITSUBISHI ENGINEERING-PLASTICS CORPORATION (JP) 2026-05-07 US disclosed
EP-4692233-A1 POLYCARBONATE RESIN COMPOSITION Mitsubishi Engineering-Plastics Corporation (JP) 2026-02-11 EP disclosed
US-20260015500-A1 POLYCARBONATE RESIN COMPOSITION AND MOLDED ARTICLE MITSUBISHI ENGINEERING-PLASTICS CORPORATION (JP) 2026-01-15 US disclosed
EP-4674907-A1 RESIN COMPOSITION AND RESIN MOLDED ARTICLE Konica Minolta, Inc. (JP) 2026-01-07 EP disclosed
US-12460048-B2 Thermoplastic resin composition and formed product MITSUBISHI CHEMICAL CORPORATION (JP) 2025-11-04 US disclosed
EP-4596628-A1 POLYCARBONATE RESIN COMPOSITION Mitsubishi Engineering-Plastics Corporation (JP) 2025-08-06 EP disclosed
EP-4563655-A1 POLYCARBONATE RESIN COMPOSITION AND MOLDED ARTICLE Mitsubishi Engineering-Plastics Corporation (JP) 2025-06-04 EP disclosed
EP-0469403-B1 High molecular weight polyester based on 1,1-bis-(4-hydroxyphenyl)-alkylcycloalkanes and thermoplastic blends thereof BAYER AG (DE) 1996-02-28 EP disclosed
EP-0469404-B1 Polyestercarbonates based on 1,1-bis-(4-hydroxyphenyl)-alkylcycloalkanes and thermoplastic blends thereof BAYER AG (DE) 1996-02-28 EP disclosed
US-5430195-A Diamino compounds and liquid crystal aligning films CHISSO CORPORATION (JP) 1995-07-04 US disclosed
US-5414126-A Diamino compounds and liquid crystal aligning films CHISSO CORPORATION (JP) 1995-05-09 US disclosed
EP-0469404-A2 Polyestercarbonates based on 1,1-bis-(4-hydroxyphenyl)-alkylcycloalkanes and thermoplastic blends thereof BAYER AG (DE) 1992-02-05 EP disclosed
EP-0465967-A2 Continuous separation of aromatic polycarbonates in semicrystalline form from CH2Cll2 solutions BAYER AG (DE) 1992-01-15 EP disclosed
US-5034457-A Polycarbonate for use in molding materials for laminated films and for electronics BAYER AKTIENGESELLSCHAFT (DE) 1991-07-23 US disclosed
US-5010163-A Molding materials BAYER AKTIENGESELLSCHAFT (DE) 1991-04-23 US disclosed
EP-0387593-A2 Thermoplastic alloys of polycarbonates based on substituted cyclohexylidenbisphenols BAYER AG (DE) 1990-09-19 EP disclosed
EP-0374630-A2 Polycarbonates from cyclohexylidene diphenols BAYER AG (DE) 1990-06-27 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260125537-A1 POLYCARBONATE RESIN COMPOSITION COL1A1, RER1, GSTP1 ESR2 550/4885ESR1 990/4885DEGS1 1483/4885
US-20260015500-A1 POLYCARBONATE RESIN COMPOSITION AND MOLDED ARTICLE CHERP, RER1, TAF1 ESR2 861/4885ESR1 602/4885DEGS1 1696/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.