SCHEMBL157149

SCHEMBL157149

Oc1ccc(C2(c3ccccc3)CCC(O)CC2)cc1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR2 Q92731 6/20 0.53
ESR1 P03372 4/20 0.53
OPRM1 P35372 2/20 0.42
MEN1 O00255 1/20 0.41
CYP2C9 P11712 1/20 0.41
KMT2A Q03164 1/20 0.41
MAPK1 P28482 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
SLC6A4 P31645 3/20 0.40
SLC6A3 Q01959 3/20 0.40
MAPT P10636 1/20 0.38
ALOX5AP P20292 1/20 0.38
AKR1B1 P15121 1/20 0.38
GRIN2D O15399 1/20 0.37
GRIN3B O60391 1/20 0.37
CHRM2 P08172 1/20 0.37
CHRM1 P11229 1/20 0.37
GRIN1 Q05586 1/20 0.37
KCNH2 Q12809 1/20 0.37
GRIN2A Q12879 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8908857 0.92 ESR2 (0.61) ESR2ESR1SLC6A4SLC6A3
SCHEMBL1046438 0.90 OPRM1 (0.50) OPRM1MEN1CYP2C9KMT2AMAPK1
SCHEMBL30738223 0.84 ESR1 (0.67) ESR2ESR1OPRM1MEN1CYP2C9
SCHEMBL8148479 0.81 ESR2 (0.53) ESR2ESR1SLC6A4SLC6A3
SCHEMBL2473994 0.80 ESR1 (0.83) ESR2ESR1OPRM1MEN1CYP2C9
SCHEMBL2045808 0.80 ESR2 (0.52) ESR2ESR1CYP2C9CYP2D6
SCHEMBL12893332 0.80 ESR2 (0.47) ESR2ESR1OPRM1MEN1CYP2C9
SCHEMBL20684752 0.80 ESR2 (0.47) ESR2ESR1OPRM1MEN1CYP2C9
SCHEMBL12893338 0.80 ESR2 (0.47) ESR2ESR1OPRM1MEN1CYP2C9
SCHEMBL1256648 0.80 ESR2 (0.47) ESR2ESR1OPRM1MEN1CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1256 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023194099-A1 A TWO-PART, ROOM TEMPERATURE CURABLE HEAT AND FIRE RETARDANT COMPOSITION HENKEL AG & CO. KGAA (DE) 2023-10-12 WO claimed
US-11542268-B2 Cationically curable compositions with latent reducing agent demonstrating low cure temperature HENKEL AG & CO. KGAA (DE) 2023-01-03 US claimed
CN-113150550-B High-rigidity high-temperature-resistant PPS modified material and preparation method thereof 深圳市高科塑化有限公司 2022-08-16 CN claimed
WO-2022100867-A1 POLYMER AS UNIVERSAL DISPERSANT FOR PIGMENTS IN COLORANT OR COATING COMPOSITION RHODIA OPERATIONS (FR) 2022-05-19 WO claimed
EP-2596029-B1 MODIFIED PERFLUOROPLASTICS, METHOD FOR PRODUCING SAME, AND USE THEREOF LEIBNIZ INST POLYMERFORSCHUNG DRESDEN EV (DE) 2022-04-06 EP claimed
US-20210284881-A1 Fast Curing Epoxy Acrylic Liquid Shim Henkel IP & Holding GmbH (DE) 2021-09-16 US claimed
CN-113150550-A High-rigidity high-temperature-resistant PPS modified material and preparation method thereof 深圳市高科塑化有限公司 2021-07-23 CN claimed
EP-3842466-A1 PRODUCT OF GLYCIDYL ETHER OF A MONO OR POLYHYDRIC PHENOL, EPOXY RESIN COMPOSITION, AND PROCESS FOR PRODUCING PRODUCT OF GLYCIDYL ETHER OF A MONO OR POLYHYDRIC PHENOL Chang Chun Plastics Co., Ltd. (TW) 2021-06-30 EP claimed
EP-3827063-A1 FAST CURING EPOXY ACRYLIC LIQUID SHIM Henkel IP & Holding GmbH (DE) 2021-06-02 EP claimed
US-20210107915-A1 CATIONICALLY CURABLE COMPOSITIONS WITH LATENT REDUCING AGENT DEMONSTRATING LOW CURE TEMPERATURE HENKEL AG & CO. KGAA (DE) 2021-04-15 US claimed
JP-2001506313-A 2001-05-15 JP claimed
EP-0929592-A4 THERMOSETTING RESIN COMPOSITIONS USEFUL AS UNDERFILL SEALANTS LOCTITE CORP (US) 2000-09-13 EP claimed
WO-2000040634-A2 MODIFIED EPOXIES FOR PAPER SIZING HERCULES INCORPORATED (US) 2000-07-13 WO claimed
EP-0929592-A1 THERMOSETTING RESIN COMPOSITIONS USEFUL AS UNDERFILL SEALANTS LOCTITE CORPORATION (US) 1999-07-21 EP claimed
US-5925725-A WATER DILUTABLE EPOXY RESINS VIANOVA RESINS GMBH (DE) 1999-07-20 US claimed
WO-1999005196-A1 THERMOSETTING RESIN COMPOSITIONS USEFUL AS UNDERFILL SEALANTS LOCTITE CORPORATION (US) 1999-02-04 WO claimed
US-5681128-A ADHESIVE COMPRISING CURED RESIN ADHESIVELY BONDING MARKER TO SURFACE ILLINOIS TOOL WORKS INC. (US) 1997-10-28 US claimed
US-5407994-A With epoxy/isocyanurate resin; toughness, increased melt viscosity BAYER AKTIENGESELLSCHAFT (DE) 1995-04-18 US claimed
US-4229330-A REACTING A CARBOPHENOLIC DIOL WITH AN EPOXIDIZED VEGETABLE OIL AND THEN REACTING WITH PHENOLS AND FORMALDEHYDE HITACHI CHEMICAL COMPANY, LTD. (JP) 1980-10-21 US claimed
US-3960968-A SPRAYING ONTO A TURBULENT LIQUID FILM OF ALKALI HYDROXIDE BAYER AKTIENGESELLSCHAFT (DT) 1976-06-01 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11542268-B2 Cationically curable compositions with latent reducing agent demonstrating low cure temperature CHIT1, SGMS2, LTA ESR2 4017/4885ESR1 3732/4885OPRM1 4666/4885
US-20210107915-A1 CATIONICALLY CURABLE COMPOSITIONS WITH LATENT REDUCING AGENT DEMONSTRATING LOW CURE TEMPERATURE CHIT1, SGMS2, LTA ESR2 4017/4885ESR1 3732/4885OPRM1 4666/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.