Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | AKT1 | P31749 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.31 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.31 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.31 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.30 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.30 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.30 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.30 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4298117 | 0.82 | CA12 (0.39) | ALDH1A1CA12CA1CA2CA9 | |
| SCHEMBL173453 | 0.77 | CA12 (0.38) | ALDH1A1CA12CA1CA2CA9 | |
| SCHEMBL161425 | 0.74 | CA1 (0.42) | ALDH1A1CA12CA1CA2CA9 | |
| SCHEMBL11869464 | 0.73 | IDO1 (0.57) | ALDH1A1 | |
| SCHEMBL14732590 | 0.73 | ALDH1A1 (0.34) | ALDH1A1MEN1KMT2AHDAC3HDAC1 | |
| SCHEMBL10911565 | 0.73 | POLB (0.40) | ALDH1A1CA12CA1CA2CA9 | |
| SCHEMBL4631666 | 0.73 | CYP1A2 (0.43) | ALDH1A1MEN1NPC1RAB9AKMT2A | |
| SCHEMBL164079 | 0.73 | CA12 (0.41) | ALDH1A1CA12CA1CA2CA9 | |
| SCHEMBL24633983 | 0.72 | CA12 (0.33) | CA12CA1CA2CA9HDAC3 | |
| SCHEMBL27401002 | 0.71 | HDAC3 (0.36) | ALDH1A1CA12CA1CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8883912-B2 | Synthesis of arborescent polymers via controlled inimer-type reversible addition-fragmentation chain transfer (RAFT) polymerization | UNIVERSITY OF AKRON (US) | 2014-11-11 | — | — | US | disclosed |
| US-20110144268-A1 | SYNTHESIS OF ARBORESCENT POLYMERS VIA CONTROLLED INIMER-TYPE REVERSIBLE ADDITION-FRAGMENTATION CHAIN TRANSFER (RAFT) POLYMERIZATION | THE UNIVERSITY OF AKRON (US) | 2011-06-16 | — | — | US | disclosed |
| US-7714075-B1 | Polymerization with living characteristics | COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) | 2010-05-11 | — | — | US | disclosed |
| US-7666962-B2 | Polymerization with living characteristics | COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) | 2010-02-23 | — | — | US | disclosed |
| WO-2010019563-A1 | SYNTHESIS OF ARBORESCENT POLYMERS VIA CONTROLLED INIMER-TYPE REVERSIBLE ADDITION-FRAGMENTATION CHAIN TRANSFER (RAFT) POLYMERIZATION | THE UNIVERSITY OF AKRON (US) | 2010-02-18 | — | — | WO | disclosed |
| US-7662986-B2 | Polymerization with living characteristics | COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) | 2010-02-16 | — | — | US | disclosed |
| US-20080139836-A1 | Polymerization with living characteristics | LE TAM PHUONG | 2008-06-12 | — | — | US | disclosed |
| US-20080139764-A1 | Polymerization with living characteristics | COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) | 2008-06-12 | — | — | US | disclosed |
| US-7250479-B2 | Polymerization with living characteristics | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2007-07-31 | — | — | US | disclosed |
| US-20040171777-A1 | Polymerization with living characteristics | COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) | 2004-09-02 | — | — | US | disclosed |
| EP-0910587-B1 | POLYMERIZATION WITH LIVING CHARACTERISTICS | DU PONT (US) | 2001-12-12 | — | — | EP | disclosed |
| EP-0910587-A1 | POLYMERIZATION WITH LIVING CHARACTERISTICS | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1999-04-28 | — | — | EP | disclosed |
| WO-1998001478-A1 | POLYMERIZATION WITH LIVING CHARACTERISTICS | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1998-01-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080139836-A1 | Polymerization with living characteristics | UQCRB, MTR, UQCRC2 | ALDH1A1 1639/4885CA12 1009/4885CA1 698/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.