Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDB1 | Q16531 | 8/20 | 0.48 |
| ▸ | CRBN | Q96SW2 | 8/20 | 0.48 |
| ▸ | GPR119 | Q8TDV5 | 6/20 | 0.41 |
| ▸ | PIK3CD | O00329 | 3/20 | 0.36 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.35 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20231736 | 0.74 | DDB1 (0.44) | DDB1CRBNGPR119PIK3CDPIK3CA | |
| SCHEMBL20463155 | 0.73 | GPR119 (0.46) | GPR119PIK3CDPIK3CAHSD11B1 | |
| SCHEMBL20231730 | 0.73 | DDB1 (0.42) | DDB1CRBNGPR119PIK3CDPIK3CA | |
| SCHEMBL25074070 | 0.71 | DDB1 (0.60) | DDB1CRBNGPR119 | |
| SCHEMBL30201818 | 0.71 | DDB1 (0.60) | DDB1CRBNGPR119 | |
| SCHEMBL20463158 | 0.69 | GPR119 (0.40) | GPR119PIK3CDPIK3CAHSD11B1 | |
| SCHEMBL28666815 | 0.69 | GPR119 (0.52) | GPR119PIK3CDPIK3CA | |
| SCHEMBL28666814 | 0.69 | GPR119 (0.52) | GPR119PIK3CDPIK3CA | |
| SCHEMBL21887083 | 0.69 | GPR119 (0.59) | GPR119PIK3CDPIK3CA | |
| SCHEMBL20234855 | 0.69 | GPR119 (0.59) | GPR119PIK3CDPIK3CA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018144649-A1 | CEREBLON LIGANDS AND BIFUNCTIONAL COMPOUNDS COMPRISING THE SAME | Arvinas, Inc. (US) | 2018-08-09 | — | — | WO | disclosed |