Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 5/20 | 0.39 |
| ▸ | MTNR1B | P49286 | 5/20 | 0.39 |
| ▸ | ACHE | P22303 | 3/20 | 0.38 |
| ▸ | BCHE | P06276 | 2/20 | 0.38 |
| ▸ | FAAH | O00519 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20463237 | 0.85 | MTNR1A (0.42) | MTNR1AMTNR1BACHEBCHEFAAH | |
| SCHEMBL2701465 | 0.79 | GSK3B (0.46) | — | |
| SCHEMBL1068246 | 0.79 | GSK3B (0.46) | — | |
| SCHEMBL2701471 | 0.79 | GSK3B (0.46) | — | |
| SCHEMBL1066400 | 0.74 | ALDH1A1 (0.45) | MTNR1AMTNR1BL3MBTL1CYP1A2MAPT | |
| SCHEMBL1066397 | 0.74 | ALDH1A1 (0.45) | MTNR1AMTNR1BL3MBTL1CYP1A2MAPT | |
| SCHEMBL1066395 | 0.74 | ALDH1A1 (0.45) | MTNR1AMTNR1BL3MBTL1CYP1A2MAPT | |
| SCHEMBL5933894 | 0.74 | ACHE (0.62) | MTNR1AMTNR1BACHEBCHEFAAH | |
| SCHEMBL30519844 | 0.74 | ACHE (0.62) | MTNR1AMTNR1BACHEBCHEFAAH | |
| SCHEMBL1068138 | 0.73 | LMNA (0.49) | BCHEL3MBTL1GAAMAPTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018144649-A1 | CEREBLON LIGANDS AND BIFUNCTIONAL COMPOUNDS COMPRISING THE SAME | Arvinas, Inc. (US) | 2018-08-09 | — | — | WO | disclosed |