Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 6/20 | 0.42 |
| ▸ | MTNR1B | P49286 | 6/20 | 0.42 |
| ▸ | ACHE | P22303 | 4/20 | 0.40 |
| ▸ | BCHE | P06276 | 3/20 | 0.40 |
| ▸ | FAAH | O00519 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | MARK4 | Q96L34 | 1/20 | 0.36 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20463239 | 0.85 | MTNR1A (0.39) | MTNR1AMTNR1BACHEBCHEFAAH | |
| SCHEMBL30519844 | 0.76 | ACHE (0.62) | MTNR1AMTNR1BACHEBCHEFAAH | |
| SCHEMBL5933894 | 0.76 | ACHE (0.62) | MTNR1AMTNR1BACHEBCHEFAAH | |
| SCHEMBL1067886 | 0.74 | MGLL (0.47) | — | |
| SCHEMBL1067883 | 0.74 | MGLL (0.47) | — | |
| SCHEMBL1067887 | 0.74 | MGLL (0.47) | — | |
| SCHEMBL18713611 | 0.72 | ACHE (0.43) | MTNR1AMTNR1BACHEBCHEFAAH | |
| SCHEMBL29110950 | 0.72 | L3MBTL1 (0.56) | MTNR1AMTNR1BL3MBTL1AOC3 | |
| SCHEMBL13814395 | 0.71 | AOC3 (0.51) | MTNR1AMTNR1BACHEL3MBTL1AOC3 | |
| SCHEMBL1064148 | 0.71 | ALDH1A1 (0.48) | MTNR1AMTNR1BL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018144649-A1 | CEREBLON LIGANDS AND BIFUNCTIONAL COMPOUNDS COMPRISING THE SAME | Arvinas, Inc. (US) | 2018-08-09 | — | — | WO | disclosed |