Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FLT3 | P36888 | 1/20 | 0.53 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.47 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.42 |
| ▸ | AHR | P35869 | 1/20 | 0.42 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.42 |
| ▸ | AXL | P30530 | 1/20 | 0.42 |
| ▸ | IDO1 | P14902 | 1/20 | 0.40 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.40 |
| ▸ | NOS1 | P29475 | 1/20 | 0.40 |
| ▸ | METAP2 | P50579 | 1/20 | 0.40 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
| ▸ | IDH1 | O75874 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.38 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.38 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL826338 | 0.78 | FLT3 (0.51) | FLT3CYP2A6AXLMEN1KMT2A | |
| SCHEMBL27948497 | 0.77 | CYP2A6 (0.58) | CYP2A6AXLHRH4MEN1KMT2A | |
| SCHEMBL15690453 | 0.75 | FLT3 (0.51) | FLT3CYP19A1HRH4HRH3IDH1 | |
| SCHEMBL3381954 | 0.75 | FLT3 (0.48) | FLT3CYP19A1CYP2A6AHRNR4A2 | |
| SCHEMBL29056767 | 0.74 | FLT3 (0.47) | FLT3CYP19A1CYP2A6AHRNR4A2 | |
| SCHEMBL29614783 | 0.74 | KDM4E (0.53) | FLT3CYP2A6MEN1KMT2ALOXL2 | |
| SCHEMBL827599 | 0.74 | KDM4E (0.53) | FLT3CYP2A6MEN1KMT2ALOXL2 | |
| SCHEMBL10246 | 0.74 | CYP2A6 (0.59) | FLT3CYP19A1CYP2A6AHRNR4A2 | |
| SCHEMBL18886841 | 0.73 | GABRA1 (0.46) | FLT3HRH4HRH3PDGFRBKDM4E | |
| SCHEMBL21812417 | 0.73 | CYP19A1 (0.55) | FLT3CYP19A1CYP2A6AHRNR4A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180222860-A1 | MODULATORS OF ROR-GAMMA | VITAE PHARMACEUTICALS, LLC | 2018-08-09 | — | — | US | disclosed |
| CN-106928121-A | The high efficiency preparation method of 3- substitution-benzo five-membered heterocycle -2- carbonyls | 暨南大学 | 2017-07-07 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180222860-A1 | MODULATORS OF ROR-GAMMA | RORB, RORC, RORA | FLT3 1365/4885CYP19A1 317/4885CYP2A6 309/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.