Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 6/20 | 0.37 |
| ▸ | SSTR5 | P35346 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | AVPR1A | P37288 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | NPY5R | Q15761 | 3/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16775287 | 0.80 | PRMT1 (0.40) | NPSR1SSTR5CYP2C9CYP2C19CYP3A4 | |
| SCHEMBL16755703 | 0.71 | CYP3A4 (0.44) | CYP3A4HTTSMN1; SMN2AVPR1AGAA | |
| SCHEMBL16772471 | 0.71 | PRMT1 (0.42) | NPSR1L3MBTL1SMN1; SMN2POLBAVPR1A | |
| SCHEMBL16772538 | 0.68 | MEN1 (0.59) | NPSR1CYP2C9CYP2C19CYP3A4CYP1A2 | |
| SCHEMBL16772402 | 0.67 | NPSR1 (0.45) | NPSR1CYP2C19CYP3A4HTTL3MBTL1 | |
| SCHEMBL20080293 | 0.64 | MAPT (0.56) | NPSR1CYP2C19CYP3A4HTTL3MBTL1 | |
| SCHEMBL9038970 | 0.64 | CYP3A4 (0.46) | NPSR1SSTR5CYP2C9CYP2C19CYP3A4 | |
| SCHEMBL20468616 | 0.64 | MAPT (0.39) | NPSR1CYP2C19CYP3A4HTTL3MBTL1 | |
| SCHEMBL9039746 | 0.62 | HCAR2 (0.54) | NPSR1CYP3A4L3MBTL1SMN1; SMN2POLB | |
| SCHEMBL18932748 | 0.61 | AKR1C1 (0.68) | NPSR1CYP2C9CYP2C19CYP3A4CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180222880-A1 | SecA INHIBITORS AND METHODS OF MAKING AND USING THEREOF | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2018-08-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180222880-A1 | SecA INHIBITORS AND METHODS OF MAKING AND USING THEREOF | SEC61B, SEC61A1, SEC23A | NPSR1 4121/4885SSTR5 4156/4885CYP2C9 2821/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.