SCHEMBL2047154

SCHEMBL2047154

CC(=N\OCc1ccccc1)/C(C)=N/OCc1ccccc1

nearest known ligand 0.50

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 5/20 0.50
RAB9A P51151 5/20 0.50
SMN1; SMN2 Q16637 3/20 0.50
L3MBTL1 Q9Y468 3/20 0.50
ALDH1A1 P00352 2/20 0.50
TSHR P16473 2/20 0.46
MAPT P10636 1/20 0.45
ALOX5 P09917 1/20 0.45
LMNA P02545 3/20 0.44
MAPK1 P28482 1/20 0.44
HTT P42858 1/20 0.44
IDO1 P14902 1/20 0.43
PPARG P37231 2/20 0.43
PPARA Q07869 1/20 0.43
CYP3A4 P08684 1/20 0.42
CYP2C9 P11712 1/20 0.42
CYP2C19 P33261 1/20 0.42
MAOB P27338 1/20 0.42
AGXT P21549 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2047156 1.00 NPC1 (0.50) NPC1RAB9ASMN1; SMN2L3MBTL1ALDH1A1
SCHEMBL1629181 0.88 ALDH1A1 (0.53) NPC1RAB9ASMN1; SMN2L3MBTL1ALDH1A1
SCHEMBL934853 0.88 ALOX5 (0.56) NPC1RAB9ASMN1; SMN2L3MBTL1ALDH1A1
SCHEMBL934854 0.88 ALOX5 (0.56) NPC1RAB9ASMN1; SMN2L3MBTL1ALDH1A1
SCHEMBL1629179 0.88 ALDH1A1 (0.53) NPC1RAB9ASMN1; SMN2L3MBTL1ALDH1A1
SCHEMBL9900542 0.88 ALDH1A1 (0.53) NPC1RAB9ASMN1; SMN2L3MBTL1ALDH1A1
SCHEMBL678711 0.87 MAPT (0.57) NPC1RAB9ASMN1; SMN2L3MBTL1ALDH1A1
SCHEMBL408656 0.85 ALDH1A1 (0.50) NPC1RAB9ASMN1; SMN2L3MBTL1ALDH1A1
SCHEMBL408659 0.85 ALDH1A1 (0.50) NPC1RAB9ASMN1; SMN2L3MBTL1ALDH1A1
SCHEMBL2047751 0.85 NPC1 (0.43) NPC1RAB9ASMN1; SMN2L3MBTL1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8338544-B2 Polymers functionalized with polyoxime compounds and methods for their manufacture BRIDGESTONE CORPORATION (JP) 2012-12-25 US claimed
US-20110152449-A1 POLYMERS FUNCTIONALIZED WITH POLYOXIME COMPOUNDS AND METHODS FOR THEIR MANUFACTURE BRIDGESTONE CORPORATION (JP) 2011-06-23 US claimed
CN-100364493-B9 Water absorbing agent and preparation method thereof, absorber and absorbent commodity using the water absorbing agent SDP GLOBAL Co.,Ltd. (JP) 2019-11-08 CN disclosed
US-8338544-B2 Polymers functionalized with polyoxime compounds and methods for their manufacture BRIDGESTONE CORPORATION (JP) 2012-12-25 US disclosed
EP-2516475-A1 POLYMERS FUNCTIONALIZED WITH POLYOXIME COMPOUNDS AND METHODS FOR THEIR MANUFACTURE Bridgestone Corporation (JP) 2012-10-31 EP disclosed
US-20110152449-A1 POLYMERS FUNCTIONALIZED WITH POLYOXIME COMPOUNDS AND METHODS FOR THEIR MANUFACTURE BRIDGESTONE CORPORATION (JP) 2011-06-23 US disclosed
CN-1589304-A Water-absorbing agent, method for producing same, and absorbent article using same SAN DIA POLYMERS LTD (JP) 2005-03-02 CN disclosed
CN-1443092-A Absorbents and process for producing same, absorbable constructs and absorbable articles SANYO CHEMICAL IND LTD (JP) 2003-09-17 CN disclosed