SCHEMBL9900542

SCHEMBL9900542

CC(=O)/C(C)=N/OCc1ccccc1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.53
ALOX5 P09917 1/20 0.47
NPC1 O15118 2/20 0.45
RAB9A P51151 2/20 0.45
L3MBTL1 Q9Y468 2/20 0.45
SMN1; SMN2 Q16637 1/20 0.45
PPARG P37231 2/20 0.45
PPARA Q07869 1/20 0.45
MAOB P27338 2/20 0.45
MAPK1 P28482 1/20 0.43
SLC6A2 P23975 1/20 0.43
SLC6A3 Q01959 1/20 0.43
KMT2A Q03164 1/20 0.43
TDP1 Q9NUW8 1/20 0.43
S1PR1 P21453 1/20 0.42
CA1 P00915 1/20 0.42
CA2 P00918 1/20 0.42
PTGS2 P35354 1/20 0.42
BRD4 O60885 1/20 0.41
LMNA P02545 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1629181 1.00 ALDH1A1 (0.53) ALDH1A1ALOX5NPC1RAB9AL3MBTL1
SCHEMBL1629179 1.00 ALDH1A1 (0.53) ALDH1A1ALOX5NPC1RAB9AL3MBTL1
SCHEMBL934853 0.89 ALOX5 (0.56) ALDH1A1ALOX5NPC1RAB9AL3MBTL1
SCHEMBL934854 0.89 ALOX5 (0.56) ALDH1A1ALOX5NPC1RAB9AL3MBTL1
SCHEMBL2047154 0.88 NPC1 (0.50) ALDH1A1ALOX5NPC1RAB9AL3MBTL1
SCHEMBL2047156 0.88 NPC1 (0.50) ALDH1A1ALOX5NPC1RAB9AL3MBTL1
SCHEMBL408659 0.86 ALDH1A1 (0.50) ALDH1A1ALOX5NPC1RAB9AL3MBTL1
SCHEMBL408656 0.86 ALDH1A1 (0.50) ALDH1A1ALOX5NPC1RAB9AL3MBTL1
SCHEMBL9898660 0.84 ALDH1A1 (0.49) ALDH1A1ALOX5NPC1RAB9AL3MBTL1
SCHEMBL2863838 0.84 NPC1 (0.49) ALDH1A1ALOX5NPC1RAB9AL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8748531-B2 Polymers functionalized with oxime compounds containing an acyl group BRIDGESTONE CORPORATION (JP) 2014-06-10 US claimed
EP-2649102-A1 POLYMERS FUNCTIONALIZED WITH OXIME COMPOUNDS CONTAINING AN ACYL GROUP Bridgestone Corporation (JP) 2013-10-16 EP claimed
US-20120149833-A1 POLYMERS FUNCTIONALIZED WITH OXIME COMPOUNDS CONTAINING AN ACYL GROUP BRIDGESTONE CORPORATION (JP) 2012-06-14 US claimed
WO-2012078962-A1 POLYMERS FUNCTIONALIZED WITH OXIME COMPOUNDS CONTAINING AN ACYL GROUP BRIDGESTONE CORPORATION (JP) 2012-06-14 WO claimed
EP-2649102-B1 POLYMERS FUNCTIONALIZED WITH OXIME COMPOUNDS CONTAINING AN ACYL GROUP BRIDGESTONE CORP (JP) 2014-11-26 EP disclosed
US-8748531-B2 Polymers functionalized with oxime compounds containing an acyl group BRIDGESTONE CORPORATION (JP) 2014-06-10 US disclosed
EP-2649102-A1 POLYMERS FUNCTIONALIZED WITH OXIME COMPOUNDS CONTAINING AN ACYL GROUP Bridgestone Corporation (JP) 2013-10-16 EP disclosed
US-20120149833-A1 POLYMERS FUNCTIONALIZED WITH OXIME COMPOUNDS CONTAINING AN ACYL GROUP BRIDGESTONE CORPORATION (JP) 2012-06-14 US disclosed
WO-2012078962-A1 POLYMERS FUNCTIONALIZED WITH OXIME COMPOUNDS CONTAINING AN ACYL GROUP BRIDGESTONE CORPORATION (JP) 2012-06-14 WO disclosed