SCHEMBL2047376

SCHEMBL2047376

O=C(c1ccccc1O)C1CC1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PIN1 Q13526 1/20 0.54
KDM4E B2RXH2 8/20 0.52
HPGD P15428 7/20 0.52
ALDH1A1 P00352 5/20 0.52
SMN1; SMN2 Q16637 2/20 0.52
CA12 O43570 1/20 0.52
CA1 P00915 1/20 0.52
CA2 P00918 1/20 0.52
HMGB1 P09429 1/20 0.52
CA4 P22748 1/20 0.52
CA6 P23280 1/20 0.52
CA7 P43166 1/20 0.52
CA9 Q16790 1/20 0.52
NAPRT Q6XQN6 1/20 0.52
CA14 Q9ULX7 1/20 0.52
HSD17B10 Q99714 4/20 0.50
TSHR P16473 3/20 0.50
MAPT P10636 2/20 0.50
MGLL Q99685 1/20 0.49
LMNA P02545 4/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3978477 0.90 KDM4E (0.57) PIN1KDM4EHPGDALDH1A1SMN1; SMN2
SCHEMBL29850510 0.87 KDM4E (0.52) PIN1KDM4EHPGDALDH1A1SMN1; SMN2
SCHEMBL11617232 0.87 HTR3E (0.56) PIN1KDM4EHPGDALDH1A1SMN1; SMN2
Bromide SCHEMBL7250119 0.85 HTR3E (0.55) PIN1KDM4EHPGDALDH1A1SMN1; SMN2
SCHEMBL27544614 0.84 MGLL (0.51) PIN1KDM4EHPGDALDH1A1SMN1; SMN2
SCHEMBL14390638 0.80 KDM4E (0.43) PIN1KDM4EHPGDALDH1A1HSD17B10
SCHEMBL16109177 0.79 KDM4E (0.49) PIN1KDM4EHPGDALDH1A1SMN1; SMN2
SCHEMBL6140950 0.78 CES2 (0.58) HPGDALDH1A1SMN1; SMN2TSHRMAPT
SCHEMBL11554530 0.77 MGLL (0.50) ALDH1A1MAPTMGLLLMNARAB9A
SCHEMBL6575271 0.77 HSD11B1 (0.50) KDM4EHPGDALDH1A1HSD17B10TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102666461-A Cyclic compound, process for production thereof, radiation-sensitive composition, and resist pattern formation method MITSUBISHI GAS CHEMICAL CO 2012-09-12 CN disclosed
US-7964531-B2 3-phenoxy-4-pyridazinol derivatives and herbicidal composition containing the same MITSUI CHEMICALS AGRO, INC. (JP) 2011-06-21 US disclosed
US-20100041555-A1 3-Phenoxy-4-pyridazinol derivatives and herbicidal composition containing the same MITSUI CHEMICALS AGRO, INC. (JP) 2010-02-18 US disclosed
US-7608563-B2 3-phenoxy-4-pyridazinol derivatives and herbicide composition containing the same MITSUI AGRO CHEMICALS, INC. (JP) 2009-10-27 US disclosed
EP-1426365-B9 3-PHENOXY-4-PYRIDAZINOL DERIVATIVE AND HERBICIDE COMPOSITION CONTAINING THE SAME MITSUI CHEMICALS AGRO INC (JP) 2009-10-21 EP disclosed
EP-1426365-B1 3-PHENOXY-4-PYRIDAZINOL DERIVATIVE AND HERBICIDE COMPOSITION CONTAINING THE SAME SANKYO AGRO CO LTD (JP) 2009-07-15 EP disclosed
US-20050037925-A1 3-phenoxy-4-pyridazinol derivatives and herbicide composition containing the same SANKYO AGRO COMPANY, LIMITED (JP) 2005-02-17 US disclosed
EP-1426365-A1 3-PHENOXY-4-PYRIDAZINOL DERIVATIVE AND HERBICIDE COMPOSITION CONTAINING THE SAME Sankyo Agro Company, Limited (JP) 2004-06-09 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100041555-A1 3-Phenoxy-4-pyridazinol derivatives and herbicidal composition containing the same CBR3, DDT, CBR1 PIN1 2600/4885KDM4E 923/4885HPGD 1537/4885
US-20050037925-A1 3-phenoxy-4-pyridazinol derivatives and herbicide composition containing the same CBR3, DDT, CHRM2 PIN1 2080/4885KDM4E 960/4885HPGD 1885/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.