Phosphine

Phosphine

SCHEMBL2047415

C=CC(CCCC)CCCCC.P

nearest known ligand 0.44

Full drug profile on Sugi Atlas →

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
TSHR P16473 5/20 0.44
SMN1; SMN2 Q16637 1/20 0.44
DNM1 Q05193 2/20 0.40
OPRM1 P35372 1/20 0.39
ALDH1A1 P00352 1/20 0.36
LMNA P02545 1/20 0.36
ADH1B P00325 1/20 0.34
ADH1C P00326 1/20 0.34
ADH1A P07327 1/20 0.34
ADH4 P08319 1/20 0.34
ADH7 P40394 1/20 0.34
CA2 P00918 1/20 0.34
FDPS P14324 2/20 0.33
THRB P10828 1/20 0.33
TRPA1 O75762 1/20 0.33
DDAH1 O94760 1/20 0.33
GAPDH P04406 1/20 0.33
MAPT P10636 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9015898 0.97 TSHR (0.46) TSHRSMN1; SMN2DNM1OPRM1ALDH1A1
SCHEMBL9015991 0.95 DNM1 (0.46) TSHRSMN1; SMN2DNM1OPRM1LMNA
SCHEMBL10899262 0.95 DNM1 (0.46) TSHRSMN1; SMN2DNM1OPRM1LMNA
SCHEMBL25171286 0.95 DNM1 (0.46) TSHRSMN1; SMN2DNM1OPRM1LMNA
SCHEMBL9015831 0.95 DNM1 (0.46) TSHRSMN1; SMN2DNM1OPRM1LMNA
SCHEMBL25178155 0.95 DNM1 (0.46) TSHRSMN1; SMN2DNM1OPRM1LMNA
SCHEMBL9724790 0.95 TSHR (0.42) TSHRSMN1; SMN2DNM1OPRM1ALDH1A1
SCHEMBL25172438 0.92 TSHR (0.46) TSHRSMN1; SMN2DNM1OPRM1ALDH1A1
SCHEMBL25182453 0.92 TSHR (0.46) TSHRSMN1; SMN2DNM1OPRM1ALDH1A1
SCHEMBL25181774 0.92 TSHR (0.46) TSHRSMN1; SMN2DNM1OPRM1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1167372-B1 2,2-(Diaryl)vinylphosphine compound, palladium catalyst thereof, and process for producing arylamine, diaryl, or arylalkyne with the catalyst TAKASAGO PERFUMERY CO LTD (JP) 2003-12-10 EP claimed
US-6455720-B1 AS CATALYSTS TAKASAGO INTERNATIONAL CORPORATION (JP) 2002-09-24 US claimed
US-20020058837-A1 2,2 (Diarlyl) Vinylphosphine compound, palladium catalyst thereof, and process for producing arylamine, diaryl, or arylalkyne with the catalyst TAKASAGO INTERNATIONAL CORPORATION (JP) 2002-05-16 US claimed
EP-1167372-A1 2,2-(Diaryl)vinylphosphine compound, palladium catalyst thereof, and process for producing arylamine, diaryl, or arylalkyne with the catalyst Takasago International Corporation (JP) 2002-01-02 EP claimed
US-9126892-B2 Blue fluorescence compound and organic electroluminescence device using the same LG DISPLAY CO., LTD. (KR) 2015-09-08 US disclosed
US-20120305894-A1 BLUE PHOSPHORESCENT COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE USING THE SAME LG DISPLAY CO., LTD (KR) 2012-12-06 US disclosed
US-20110156011-A1 BLUE FLUORESCENCE COMPOUND AND ORGANIC ELECTROLUMINESCENCE DEVICE USING THE SAME LG DISPLAY CO., LTD. (KR) 2011-06-30 US disclosed
US-7846558-B2 Blue light emitting compound and organic electroluminescent device using the same SFC CO., LTD. (KR) 2010-12-07 US disclosed
US-20080203905-A1 Blue light emitting compound and organic electroluminescent device using the same SFC CO., LTD. (KR) 2008-08-28 US disclosed
EP-1167372-B1 2,2-(Diaryl)vinylphosphine compound, palladium catalyst thereof, and process for producing arylamine, diaryl, or arylalkyne with the catalyst TAKASAGO PERFUMERY CO LTD (JP) 2003-12-10 EP disclosed
EP-1167372-B1 2,2-(Diaryl)vinylphosphine compound, palladium catalyst thereof, and process for producing arylamine, diaryl, or arylalkyne with the catalyst TAKASAGO PERFUMERY CO LTD (JP) 2003-12-10 EP disclosed
US-6455720-B1 AS CATALYSTS TAKASAGO INTERNATIONAL CORPORATION (JP) 2002-09-24 US disclosed
US-6455720-B1 AS CATALYSTS TAKASAGO INTERNATIONAL CORPORATION (JP) 2002-09-24 US disclosed
JP-2002187894-A 2,2-(DIARYL)VINYLPHOSPHINE COMPOUND, ITS PALLADIUM CATALYST AND METHOD FOR PRODUCING ARYLAMINE, DIARYL AND ARYLALKYNE USING THE CATALYST TAKASAGO INTERNATL CORP 2002-07-05 JP disclosed
US-20020058837-A1 2,2 (Diarlyl) Vinylphosphine compound, palladium catalyst thereof, and process for producing arylamine, diaryl, or arylalkyne with the catalyst TAKASAGO INTERNATIONAL CORPORATION (JP) 2002-05-16 US disclosed
US-20020058837-A1 2,2 (Diarlyl) Vinylphosphine compound, palladium catalyst thereof, and process for producing arylamine, diaryl, or arylalkyne with the catalyst TAKASAGO INTERNATIONAL CORPORATION (JP) 2002-05-16 US disclosed
EP-1167372-A1 2,2-(Diaryl)vinylphosphine compound, palladium catalyst thereof, and process for producing arylamine, diaryl, or arylalkyne with the catalyst Takasago International Corporation (JP) 2002-01-02 EP disclosed
EP-1167372-A1 2,2-(Diaryl)vinylphosphine compound, palladium catalyst thereof, and process for producing arylamine, diaryl, or arylalkyne with the catalyst Takasago International Corporation (JP) 2002-01-02 EP disclosed
EP-1167372-A1 2,2-(Diaryl)vinylphosphine compound, palladium catalyst thereof, and process for producing arylamine, diaryl, or arylalkyne with the catalyst Takasago International Corporation (JP) 2002-01-02 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020058837-A1 2,2 (Diarlyl) Vinylphosphine compound, palladium catalyst thereof, and process for producing arylamine, diaryl, or arylalkyne with the catalyst DDT, PDCD11, PLD2 TSHR 2225/4885SMN1; SMN2 4274/4885DNM1 427/4885
US-20120305894-A1 BLUE PHOSPHORESCENT COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE USING THE SAME C5, CLIC1, CLIC4 TSHR 1832/4885SMN1; SMN2 4029/4885DNM1 4496/4885
US-20080203905-A1 Blue light emitting compound and organic electroluminescent device using the same TYR, CYBA, CRY2 TSHR 4291/4885SMN1; SMN2 2463/4885DNM1 3881/4885
US-20110156011-A1 BLUE FLUORESCENCE COMPOUND AND ORGANIC ELECTROLUMINESCENCE DEVICE USING THE SAME KCNN2, ORAI2, ETV6 TSHR 4621/4885SMN1; SMN2 3722/4885DNM1 2033/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.