Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | APAF1 | O14727 | 1/20 | 0.42 |
| ▸ | MITF | O75030 | 1/20 | 0.42 |
| ▸ | TDP2 | O95551 | 1/20 | 0.42 |
| ▸ | NSD2 | O96028 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | MPI | P34949 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | KDR | P35968 | 4/20 | 0.36 |
| ▸ | GAA | P10253 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | FLT3 | P36888 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18497902 | 0.74 | KDM4E (0.43) | LMNAKDM4ESMN1; SMN2APAF1MITF | |
| SCHEMBL20399479 | 0.66 | LMNA (0.47) | LMNAKDM4ESMN1; SMN2APAF1MITF | |
| SCHEMBL20301070 | 0.65 | KDM4E (0.52) | LMNAKDM4ESMN1; SMN2APAF1MITF | |
| SCHEMBL2905923 | 0.65 | KDM4E (0.49) | LMNAKDM4ESMN1; SMN2APAF1MITF | |
| SCHEMBL30829063 | 0.65 | GABRG2 (0.47) | KDM4EALDH1A1PKMKDRGAA | |
| SCHEMBL20474157 | 0.65 | GABRG2 (0.47) | KDM4EALDH1A1PKMKDRGAA | |
| SCHEMBL2913499 | 0.64 | KDM4E (0.48) | LMNAKDM4ESMN1; SMN2APAF1MITF | |
| SCHEMBL30829062 | 0.64 | GABRG2 (0.46) | KDM4EALDH1A1PKMKDRGAA | |
| SCHEMBL20474224 | 0.64 | GABRG2 (0.46) | KDM4EALDH1A1PKMKDRGAA | |
| SCHEMBL20300796 | 0.64 | TGFBR1 (0.47) | LMNAKDM4ESMN1; SMN2APAF1MITF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3929197-B1 | INTERMEDIATES FOR THE SYNTHESIS OF MICROBIOCIDAL HETEROBICYCLIC DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2024-03-06 | — | — | EP | disclosed |
| EP-3334736-B1 | MICROBIOCIDAL HETEROBICYCLIC DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2023-06-28 | — | — | EP | disclosed |
| EP-3929197-A1 | INTERMEDIATES FOR THE SYNTHESIS OF MICROBIOCIDAL HETEROBICYCLIC DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2021-12-29 | — | — | EP | disclosed |
| US-20210155619-A1 | MICROBIOCIDAL HETEROBICYCLIC DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2021-05-27 | — | — | US | disclosed |
| US-20210155619-A1 | MICROBIOCIDAL HETEROBICYCLIC DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2021-05-27 | — | — | US | disclosed |
| US-10906897-B2 | Microbiocidal heterobicyclic derivatives | SYNGENTA PARTICIPATIONS AG (CH) | 2021-02-02 | — | — | US | disclosed |
| US-10906897-B2 | Microbiocidal heterobicyclic derivatives | SYNGENTA PARTICIPATIONS AG (CH) | 2021-02-02 | — | — | US | disclosed |
| US-20180237434-A1 | MICROBIOCIDAL HETEROBICYCLIC DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2018-08-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10906897-B2 | Microbiocidal heterobicyclic derivatives | MSR1, C1R, C1S | LMNA 3650/4885KDM4E 3183/4885SMN1; SMN2 4806/4885 |
| US-20210155619-A1 | MICROBIOCIDAL HETEROBICYCLIC DERIVATIVES | CD14, MSR1, MPO | LMNA 3213/4885KDM4E 4810/4885SMN1; SMN2 4265/4885 |
| US-20180237434-A1 | MICROBIOCIDAL HETEROBICYCLIC DERIVATIVES | MSR1, C1R, C1S | LMNA 3650/4885KDM4E 3183/4885SMN1; SMN2 4806/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.