SCHEMBL204855

SCHEMBL204855

CC(C)=C(C(=O)O)c1ccccc1Oc1cccc(OS(=O)(=O)c2ccccc2)c1

nearest known ligand 0.48

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.48
ALDH1A1 P00352 2/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
KDM4E B2RXH2 1/20 0.40
POLB P06746 1/20 0.40
CTNNB1 P35222 1/20 0.40
PTGDR2 Q9Y5Y4 1/20 0.38
F2 P00734 1/20 0.38
GAA P10253 1/20 0.37
TSHR P16473 1/20 0.37
LMNA P02545 1/20 0.37
TDP1 Q9NUW8 1/20 0.37
GPR17 Q13304 2/20 0.36
P2RY2 P41231 1/20 0.36
FAAH O00519 1/20 0.36
SPHK2 Q9NRA0 1/20 0.36
SPHK1 Q9NYA1 1/20 0.36
MAOB P27338 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL204856 0.90 MAPT (0.45) MAPTALDH1A1SMN1; SMN2KDM4EPOLB
SCHEMBL7131300 0.89 MAPT (0.44) MAPTALDH1A1SMN1; SMN2KDM4EPOLB
SCHEMBL7131303 0.85 MAPT (0.43) MAPTALDH1A1SMN1; SMN2KDM4EPOLB
SCHEMBL2953359 0.83 MAPT (0.48) MAPTALDH1A1SMN1; SMN2KDM4EPOLB
SCHEMBL202625 0.82 KDM4E (0.59) SMN1; SMN2KDM4EPOLBCTNNB1GAA
SCHEMBL2953361 0.81 MAPT (0.45) MAPTALDH1A1SMN1; SMN2KDM4EPOLB
SCHEMBL2953357 0.81 MAPT (0.45) MAPTALDH1A1SMN1; SMN2KDM4EPOLB
SCHEMBL203717 0.80 CTNNB1 (0.59) MAPTALDH1A1SMN1; SMN2CTNNB1GAA
SCHEMBL204354 0.80 L3MBTL1 (0.44) KDM4EPOLBCTNNB1GAATSHR
SCHEMBL203988 0.80 KDM4E (0.44) MAPTALDH1A1SMN1; SMN2KDM4EPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11185074-B2 Microbiocidal quinoline (thio)carboxamide derivatives SYNGENTA PARTICIPATIONS AG (CH) 2021-11-30 US disclosed
US-20150144027-A1 PARTICULATE WOOD PRESERVATIVE AND METHOD FOR PRODUCING THE SAME KOPPERS INC. (F/K/A KOPPERS INDUSTRIES, INC.) 2015-05-28 US disclosed
US-8409627-B2 Particulate wood preservative and method for producing the same OSMOSE, INC. (US) 2013-04-02 US disclosed
US-8088801-B2 Aryloazol-2-yl cyanoethylamino compounds, method of making and method of using thereof MERIAL LIMITED (US) 2012-01-03 US disclosed
EP-1755841-B1 TREATMENT OF WOOD WITH AN INJECTABLE WOOD PRESERVATIVE SLURRY HAVING BIOCIDAL PARTICLES OSMOSE INC (US) 2010-09-15 EP disclosed
US-20090293761-A1 Composition for wood treatment comprising an injectable aqueous wood preservative slurry having sparingly-soluble biocidal particles and pigments OSMOSE, INC. 2009-12-03 US disclosed
US-20090280185-A1 Particulate wood preservative and method for producing the same PHIBROWOOD, LLC (US) 2009-11-12 US disclosed
EP-1651401-B1 PARTICULATE WOOD PRESERVATIVE AND METHOD FOR PRODUCING SAME PHIBROWOOD LLC (US) 2009-07-22 EP disclosed
EP-1796885-A1 TREATMENT OF WOOD WITH AN INJECTABLE WOOD PRESERVATIVE SLURRY HAVING BIOCIDAL PARTICLES Phibro-Tech, Inc. (US) 2007-06-20 EP disclosed
EP-1755841-A2 TREATMENT OF WOOD WITH AN INJECTABLE WOOD PRESERVATIVE SLURRY HAVING BIOCIDAL PARTICLES Phibro-Tech, Inc. (US) 2007-02-28 EP disclosed
WO-1996032235-A1 TIMBER PRESERVATIVE CONTAINING A COPPER COMPOUND BAYER AKTIENGESELLSCHAFT (DE) 1996-10-17 WO disclosed
EP-0730517-A1 TIMBER PRESERVATIVE CONTAINING A COPPER COMPOUND BAYER AG (DE) 1996-09-11 EP disclosed
EP-0714420-A1 MOULD-RESISTANT EMULSION PAINTS BAYER AG (DE) 1996-06-05 EP disclosed
EP-0705160-A1 FUNGICIDAL ACTIVE-SUBSTANCE COMBINATION BAYER AG (DE) 1996-04-10 EP disclosed
WO-1995034204-A1 BACTERICIDE THIADIAZOLIDINONES BAYER AKTIENGESELLSCHAFT (DE) 1995-12-21 WO disclosed
WO-1995024997-A1 COMBINATIONS OF ACTIVE INSECTICIDE SUBSTANCES BAYER AKTIENGESELLSCHAFT (DE) 1995-09-21 WO disclosed
WO-1995014558-A1 TIMBER PRESERVATIVE CONTAINING A COPPER COMPOUND BAYER AKTIENGESELLSCHAFT (DE) 1995-06-01 WO disclosed
WO-1995011786-A1 TIMBER PROTECTING MEDIUM CONTAINING A COPPER COMPOUND BAYER AKTIENGESELLSCHAFT (DE) 1995-05-04 WO disclosed
WO-1995006091-A1 MOULD-RESISTANT EMULSION PAINTS BAYER AKTIENGESELLSCHAFT (DE) 1995-03-02 WO disclosed
WO-1995000303-A1 FUNGICIDAL ACTIVE-SUBSTANCE COMBINATION BAYER AKTIENGESELLSCHAFT (DE) 1995-01-05 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11185074-B2 Microbiocidal quinoline (thio)carboxamide derivatives IFNG, TLR1, IDO1 MAPT 3249/4885ALDH1A1 1059/4885SMN1; SMN2 4749/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.