Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.40 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.38 |
| ▸ | F2 | P00734 | 1/20 | 0.38 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.37 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.37 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | GPR17 | Q13304 | 2/20 | 0.36 |
| ▸ | P2RY2 | P41231 | 1/20 | 0.36 |
| ▸ | FAAH | O00519 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2953361 | 0.90 | MAPT (0.45) | MAPTALDH1A1SMN1; SMN2KDM4EPOLB | |
| SCHEMBL2953357 | 0.90 | MAPT (0.45) | MAPTALDH1A1SMN1; SMN2KDM4EPOLB | |
| SCHEMBL204855 | 0.83 | MAPT (0.48) | MAPTALDH1A1SMN1; SMN2KDM4EPOLB | |
| SCHEMBL9152637 | 0.83 | MAPT (0.44) | MAPTALDH1A1SMN1; SMN2KDM4EPOLB | |
| SCHEMBL204854 | 0.83 | MAPT (0.44) | MAPTALDH1A1SMN1; SMN2KDM4EPOLB | |
| SCHEMBL29709963 | 0.83 | MAPT (0.44) | MAPTALDH1A1SMN1; SMN2KDM4EPOLB | |
| SCHEMBL2107594 | 0.82 | KDM4E (0.59) | ALDH1A1KDM4EPOLBCTNNB1MTNR1B | |
| SCHEMBL2855939 | 0.82 | KDM4E (0.59) | ALDH1A1KDM4EPOLBCTNNB1MTNR1B | |
| SCHEMBL204856 | 0.81 | MAPT (0.45) | MAPTALDH1A1SMN1; SMN2KDM4EPOLB | |
| SCHEMBL2847810 | 0.80 | CTNNB1 (0.59) | MAPTALDH1A1SMN1; SMN2POLBCTNNB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11882834-B2 | Microbiocidal thiazole derivatives | SYNGENTA PARTICIPATIONS AG (CH) | 2024-01-30 | — | — | US | disclosed |
| US-11629138-B2 | Microbiocidal picolinamide derivatives | SYNGENTA PARTICIPATIONS AG (CH) | 2023-04-18 | — | — | US | disclosed |
| US-11629129-B2 | Microbiocidal picolinamide derivatives | SYNGENTA PARTICIPATIONS AG (CH) | 2023-04-18 | — | — | US | disclosed |
| US-11566140-B2 | Exterior coating composition | TROY CORPORATION (US) | 2023-01-31 | — | — | US | disclosed |
| US-20220279703-A1 | APPARATUS AND METHOD FOR REDUCING DUST DEVELOPMENT IN PRECISION DRILL SOWING | SYNGENTA PARTICIPATIONS AG (CH) | 2022-09-08 | — | — | US | disclosed |
| US-20210186022-A1 | MICROBIOCIDAL THIAZOLE DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2021-06-24 | — | — | US | disclosed |
| US-20210114984-A1 | MICROBIOCIDAL PICOLINAMIDE DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2021-04-22 | — | — | US | disclosed |
| WO-2020243293-A1 | EXTERIOR COATING COMPOSITION | TROY CORPORATION (US) | 2020-12-03 | — | — | WO | disclosed |
| US-20200377738-A1 | EXTERIOR COATING COMPOSITION | TROY CORPORATION (US) | 2020-12-03 | — | — | US | disclosed |
| US-20200281201-A1 | MICROBIOCIDAL QUINOLINE (THIO)CARBOXAMIDE DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2020-09-10 | — | — | US | disclosed |
| US-20150133506-A1 | 1-ARYL-5-ALKYL PYRAZOLE DERIVATIVE COMPOUNDS, PROCESSES OF MAKING AND METHODS OF USING THEREOF | AVENTIS AGRICULTURE (FR) | 2015-05-14 | — | — | US | disclosed |
| US-8822689-B2 | Aryloazol-2-yl cyanoethylamino compounds, method of making and method of using thereof | MERIAL LIMITED (US) | 2014-09-02 | — | — | US | disclosed |
| US-20140080862-A1 | ARYLOAZOL-2-YL CYANOETHYLAMINO COMPOUNDS, METHOD OF MAKING AND METHOD OF USING THEREOF | AVENTIS AGRICULTURE (FR) | 2014-03-20 | — | — | US | disclosed |
| US-8314146-B2 | Thioamide compounds, method of making and method of using thereof | MERIAL LIMITED (US) | 2012-11-20 | — | — | US | disclosed |
| US-7759381-B2 | 1-aryl-5-alkyl pyrazole derivative compounds, processes of making and methods of using thereof | AVENTIS AGRICULTURE (FR) | 2010-07-20 | — | — | US | disclosed |
| US-20080312272-A1 | ARYLOAZOL-2-YL CYANOETHYLAMINO COMPOUNDS, METHOD OF MAKING AND METHOD OF USING THEREOF | MERIAL, INC. | 2008-12-18 | — | — | US | disclosed |
| US-20080031902-A1 | 1-Aryl-5-alkyl pyrazole derivative compounds, processes of making and methods of using thereof | MERIAL, INC. | 2008-02-07 | — | — | US | disclosed |
| US-6846777-B2 | Synergistic biocidal composition | THOR GMBH (DE) | 2005-01-25 | — | — | US | disclosed |
| US-20030199490-A1 | Synergistic biocidal composition | THOR GMBH (DE) | 2003-10-23 | — | — | US | disclosed |
| US-5466693-A | FOE USE IN THE CULTIVATION OF RICE | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1995-11-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (10 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11882834-B2 | Microbiocidal thiazole derivatives | MSR1, TLR1, IFNG | MAPT 4168/4885ALDH1A1 392/4885SMN1; SMN2 3617/4885 |
| US-20080031902-A1 | 1-Aryl-5-alkyl pyrazole derivative compounds, processes of making and methods of using thereof | CBR3, CBR1, NR5A2 | MAPT 4885/4885ALDH1A1 3749/4885SMN1; SMN2 3765/4885 |
| US-20080312272-A1 | ARYLOAZOL-2-YL CYANOETHYLAMINO COMPOUNDS, METHOD OF MAKING AND METHOD OF USING THEREOF | CYP4X1, CBR3, TYR | MAPT 4740/4885ALDH1A1 1677/4885SMN1; SMN2 4371/4885 |
| US-20150133506-A1 | 1-ARYL-5-ALKYL PYRAZOLE DERIVATIVE COMPOUNDS, PROCESSES OF MAKING AND METHODS OF USING THEREOF | CBR3, CBR1, NR5A2 | MAPT 4885/4885ALDH1A1 3762/4885SMN1; SMN2 3774/4885 |
| US-20210114984-A1 | MICROBIOCIDAL PICOLINAMIDE DERIVATIVES | PRF1, CASP1, MSR1 | MAPT 3592/4885ALDH1A1 1053/4885SMN1; SMN2 3416/4885 |
| US-11629138-B2 | Microbiocidal picolinamide derivatives | PRF1, CASP1, FPR1 | MAPT 3764/4885ALDH1A1 1067/4885SMN1; SMN2 3397/4885 |
| US-20140080862-A1 | ARYLOAZOL-2-YL CYANOETHYLAMINO COMPOUNDS, METHOD OF MAKING AND METHOD OF USING THEREOF | CYP4X1, CBR3, TYR | MAPT 4740/4885ALDH1A1 1677/4885SMN1; SMN2 4371/4885 |
| US-11629129-B2 | Microbiocidal picolinamide derivatives | PRF1, CASP1, MSR1 | MAPT 3592/4885ALDH1A1 1053/4885SMN1; SMN2 3416/4885 |
| US-20200281201-A1 | MICROBIOCIDAL QUINOLINE (THIO)CARBOXAMIDE DERIVATIVES | IFNG, TLR1, IDO1 | MAPT 3249/4885ALDH1A1 1059/4885SMN1; SMN2 4749/4885 |
| US-20210186022-A1 | MICROBIOCIDAL THIAZOLE DERIVATIVES | MSR1, TLR1, IFNG | MAPT 4168/4885ALDH1A1 392/4885SMN1; SMN2 3617/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.