SCHEMBL204856

SCHEMBL204856

COC(C)=C(C(=O)O)c1ccccc1Oc1cccc(OS(=O)(=O)c2ccccc2)c1

nearest known ligand 0.45

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
MAPT P10636 1/20 0.45
KDM4E B2RXH2 1/20 0.41
POLB P06746 1/20 0.41
MTNR1B P49286 1/20 0.40
P2RY2 P41231 1/20 0.39
GPR17 Q13304 1/20 0.39
ALDH1A1 P00352 3/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
RAB9A P51151 1/20 0.39
PTGDR2 Q9Y5Y4 1/20 0.38
MEN1 O00255 2/20 0.38
KMT2A Q03164 2/20 0.38
LMNA P02545 1/20 0.38
HTT P42858 1/20 0.38
ADRB3 P13945 1/20 0.38
PGR P06401 1/20 0.37
CTNNB1 P35222 1/20 0.37
TDP1 Q9NUW8 1/20 0.37
CCR2 P41597 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL204855 0.90 MAPT (0.48) MAPTKDM4EPOLBP2RY2GPR17
SCHEMBL7131303 0.86 MAPT (0.43) MAPTKDM4EPOLBMTNR1BALDH1A1
SCHEMBL7131300 0.86 MAPT (0.44) MAPTKDM4EPOLBMTNR1BALDH1A1
SCHEMBL202626 0.85 KDM4E (0.57) KDM4EPOLBMTNR1BSMN1; SMN2RAB9A
SCHEMBL203718 0.82 CTNNB1 (0.54) MAPTKDM4EALDH1A1SMN1; SMN2RAB9A
SCHEMBL204355 0.81 L3MBTL1 (0.44) KDM4EPOLBMTNR1BSMN1; SMN2RAB9A
SCHEMBL203989 0.81 KDM4E (0.44) MAPTKDM4EPOLBMTNR1BALDH1A1
SCHEMBL2953359 0.81 MAPT (0.48) MAPTKDM4EPOLBMTNR1BP2RY2
SCHEMBL203538 0.81 LMNA (0.51) MAPTKDM4EPOLBMTNR1BALDH1A1
SCHEMBL9155384 0.80 SIRT2 (0.47) MAPTKDM4EPOLBMTNR1BALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11185074-B2 Microbiocidal quinoline (thio)carboxamide derivatives SYNGENTA PARTICIPATIONS AG (CH) 2021-11-30 US disclosed
US-20150144027-A1 PARTICULATE WOOD PRESERVATIVE AND METHOD FOR PRODUCING THE SAME KOPPERS INC. (F/K/A KOPPERS INDUSTRIES, INC.) 2015-05-28 US disclosed
US-8409627-B2 Particulate wood preservative and method for producing the same OSMOSE, INC. (US) 2013-04-02 US disclosed
US-8088801-B2 Aryloazol-2-yl cyanoethylamino compounds, method of making and method of using thereof MERIAL LIMITED (US) 2012-01-03 US disclosed
EP-1755841-B1 TREATMENT OF WOOD WITH AN INJECTABLE WOOD PRESERVATIVE SLURRY HAVING BIOCIDAL PARTICLES OSMOSE INC (US) 2010-09-15 EP disclosed
US-20090293761-A1 Composition for wood treatment comprising an injectable aqueous wood preservative slurry having sparingly-soluble biocidal particles and pigments OSMOSE, INC. 2009-12-03 US disclosed
US-20090280185-A1 Particulate wood preservative and method for producing the same PHIBROWOOD, LLC (US) 2009-11-12 US disclosed
EP-1651401-B1 PARTICULATE WOOD PRESERVATIVE AND METHOD FOR PRODUCING SAME PHIBROWOOD LLC (US) 2009-07-22 EP disclosed
EP-1796885-A1 TREATMENT OF WOOD WITH AN INJECTABLE WOOD PRESERVATIVE SLURRY HAVING BIOCIDAL PARTICLES Phibro-Tech, Inc. (US) 2007-06-20 EP disclosed
EP-1755841-A2 TREATMENT OF WOOD WITH AN INJECTABLE WOOD PRESERVATIVE SLURRY HAVING BIOCIDAL PARTICLES Phibro-Tech, Inc. (US) 2007-02-28 EP disclosed
WO-1996032235-A1 TIMBER PRESERVATIVE CONTAINING A COPPER COMPOUND BAYER AKTIENGESELLSCHAFT (DE) 1996-10-17 WO disclosed
EP-0730517-A1 TIMBER PRESERVATIVE CONTAINING A COPPER COMPOUND BAYER AG (DE) 1996-09-11 EP disclosed
EP-0714420-A1 MOULD-RESISTANT EMULSION PAINTS BAYER AG (DE) 1996-06-05 EP disclosed
EP-0705160-A1 FUNGICIDAL ACTIVE-SUBSTANCE COMBINATION BAYER AG (DE) 1996-04-10 EP disclosed
WO-1995034204-A1 BACTERICIDE THIADIAZOLIDINONES BAYER AKTIENGESELLSCHAFT (DE) 1995-12-21 WO disclosed
WO-1995024997-A1 COMBINATIONS OF ACTIVE INSECTICIDE SUBSTANCES BAYER AKTIENGESELLSCHAFT (DE) 1995-09-21 WO disclosed
WO-1995014558-A1 TIMBER PRESERVATIVE CONTAINING A COPPER COMPOUND BAYER AKTIENGESELLSCHAFT (DE) 1995-06-01 WO disclosed
WO-1995011786-A1 TIMBER PROTECTING MEDIUM CONTAINING A COPPER COMPOUND BAYER AKTIENGESELLSCHAFT (DE) 1995-05-04 WO disclosed
WO-1995006091-A1 MOULD-RESISTANT EMULSION PAINTS BAYER AKTIENGESELLSCHAFT (DE) 1995-03-02 WO disclosed
WO-1995000303-A1 FUNGICIDAL ACTIVE-SUBSTANCE COMBINATION BAYER AKTIENGESELLSCHAFT (DE) 1995-01-05 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11185074-B2 Microbiocidal quinoline (thio)carboxamide derivatives IFNG, TLR1, IDO1 MAPT 3249/4885KDM4E 1828/4885POLB 1822/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.