SCHEMBL2048611

SCHEMBL2048611

O=C(O)CC(=O)C(=O)OC(CC(=O)O)C(=O)O

nearest known ligand 0.36

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.34
SLC22A6 Q4U2R8 1/20 0.32
LDHA P00338 1/20 0.32
SRR Q9GZT4 1/20 0.32
FOLH1 Q04609 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6008457 0.82 EGLN1 (0.39) TDP1SMN1; SMN2SLC22A6FOLH1
SCHEMBL6863765 0.80 TDP1 (0.40) TDP1SMN1; SMN2SLC22A6FOLH1
SCHEMBL11094949 0.80 ALOX15 (0.35) TDP1SMN1; SMN2SLC22A6
SCHEMBL2590042 0.78 TDP1 (0.39) TDP1SMN1; SMN2SLC22A6LDHASRR
SCHEMBL5404107 0.77 ALOX15 (0.38) TDP1SMN1; SMN2SLC22A6FOLH1
SCHEMBL8812874 0.75 TDP1 (0.43) TDP1SMN1; SMN2SLC22A6FOLH1
SCHEMBL895686 0.73 TSHR (0.39) TDP1SMN1; SMN2SLC22A6
SCHEMBL1828772 0.73 ALOX15 (0.36) TDP1SMN1; SMN2SLC22A6
Bicarbonate SCHEMBL6393528 0.73 TDP1 (0.42) TDP1SMN1; SMN2SLC22A6FOLH1
SCHEMBL9053647 0.72 TDP1 (0.46) TDP1SMN1; SMN2SLC22A6SRRFOLH1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 84 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9295426-B2 Detection of a physiologic parameter with a probe EXOSTAT MEDICAL, INC. (US) 2016-03-29 US claimed
US-8996090-B2 Noninvasive detection of a physiologic parameter within a body tissue of a patient EXOSTAT MEDICAL, INC. (US) 2015-03-31 US claimed
US-20140322779-A1 EUKARYOTIC ORGANISMS AND METHODS FOR INCREASING THE AVAILABILITY OF CYTOSOLIC ACETYL-COA, AND FOR THE PRODUCING 1,3-BUTANEDIOL GENOMATICA, INC. 2014-10-30 US claimed
US-20130066035-A1 EUKARYOTIC ORGANISMS AND METHODS FOR INCREASING THE AVAILABILITY OF CYTOSOLIC ACETYL-COA, AND FOR PRODUCING 1,3-BUTANEDIOL GENOMATICA, INC. (US) 2013-03-14 US claimed
US-20110152646-A1 NONINVASIVE DETECTION OF A PHYSIOLOGIC PARAMETER WITH A PROBE Vasamed Inc. (US) 2011-06-23 US claimed
EP-1534123-A4 NONINVASIVE DETECTION OF A PHYSIOLOGIC PARAMETER WITHIN A BODY TISSUE OF A PATIENT OPTICAL SENSORS INC (US) 2006-11-22 EP claimed
US-20060020179-A1 Noninvasive detection of a physiologic parameter with a probe OPTICAL SENSORS, INC. (US) 2006-01-26 US claimed
JP-2005528156-A 2005-09-22 JP claimed
EP-1534123-A2 NONINVASIVE DETECTION OF A PHYSIOLOGIC PARAMETER WITHIN A BODY TISSUE OF A PATIENT Optical Sensors Inc. (US) 2005-06-01 EP claimed
US-20040006263-A1 Noninvasive detection of a physiologic parameter within a body tissue of a patient EXOSTAT MEDICAL, INC. 2004-01-08 US claimed
WO-2003101277-A2 NONINVASIVE DETECTION OF A PHYSIOLOGIC PARAMETER WITHIN A BODY TISSUE OF A PATIENT OPTICAL SENSORS INCORPORATED (US) 2003-12-11 WO claimed
CN-118341461-A Nitrogen-doped carbon double-enzyme activity nano-enzyme and preparation method and application thereof 青岛农业大学 2024-07-16 CN disclosed
CN-115960720-A Microorganisms and methods for producing fatty alcohols of specific length and related compounds 基因组股份公司 2023-04-14 CN disclosed
CN-115812855-A Feed additive and feed for improving reproductive capacity of sows and growth performance of piglets and application of feed additive and feed 中国农业大学 2023-03-21 CN disclosed
WO-2023023538-A2 TREATING TISSUE INFLAMMATION MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH (US) 2023-02-23 WO disclosed
US-20020150627-A1 Composition containing creatine and phosphorus GENERAL NUTRITION INVESTMENT COMPANY 2002-10-17 US disclosed
EP-0188529-A4 ELECTROLYTE SOLUTIONS AND IN VITRO USE THEREOF. VEECH RICHARD L 1988-12-01 EP disclosed
EP-0188529-A1 ELECTROLYTE SOLUTIONS AND IN VITRO USE THEREOF. VEECH RICHARD L 1986-07-30 EP disclosed
WO-1986000335-A1 ELECTROLYTE SOLUTIONS AND IN VITRO USE THEREOF VEECH RICHARD L 1986-01-16 WO disclosed
US-4361570-A HUMAN AND VETERINARY MEDICINE ISTITUTO LUSO FARMACO D'ITALIA S.P.A. (IT) 1982-11-30 US disclosed