SCHEMBL6008457

SCHEMBL6008457

O=C(O)CCC(=O)C(=O)OC(CC(=O)O)C(=O)O

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
EGLN1 Q9GZT9 2/20 0.39
MAPK1 P28482 1/20 0.39
SLC13A3 Q8WWT9 1/20 0.39
OR51E2 Q9H255 1/20 0.39
FOLH1 Q04609 8/20 0.38
LMNA P02545 1/20 0.36
ALKBH5 Q6P6C2 1/20 0.36
SUCNR1 Q9BXA5 1/20 0.36
TDP1 Q9NUW8 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.33
TET2 Q6N021 3/20 0.31
KDM4A O75164 2/20 0.31
KDM4C Q9H3R0 2/20 0.31
KDM2A Q9Y2K7 2/20 0.31
TET3 O43151 1/20 0.31
SLC22A6 Q4U2R8 1/20 0.31
CYP1A2 P05177 2/20 0.30
GRM8 O00222 1/20 0.30
GRM6 O15303 1/20 0.30
GRIN2D O15399 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2048611 0.82 TDP1 (0.36) FOLH1TDP1SMN1; SMN2SLC22A6
SCHEMBL6753714 0.79 ACE (0.42) EGLN1MAPK1FOLH1LMNAALKBH5
SCHEMBL6863765 0.79 TDP1 (0.40) FOLH1LMNATDP1SMN1; SMN2SLC22A6
SCHEMBL3472423 0.76 TDP1 (0.45) EGLN1MAPK1SLC13A3OR51E2FOLH1
SCHEMBL5404107 0.75 ALOX15 (0.38) FOLH1LMNATDP1SMN1; SMN2SLC22A6
SCHEMBL8812874 0.73 TDP1 (0.43) FOLH1LMNATDP1SMN1; SMN2SLC22A6
Cadaverine Tartrate SCHEMBL7419327 0.73 ACE (0.38) EGLN1FOLH1LMNAALKBH5SUCNR1
SCHEMBL15864631 0.72 TSHR (0.47) MAPK1FOLH1LMNATDP1SLC22A6
SCHEMBL9776274 0.72 LMNA (0.44) MAPK1FOLH1LMNASLC22A6CYP1A2
SCHEMBL1828772 0.72 ALOX15 (0.36) LMNATDP1SMN1; SMN2SLC22A6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1121443-A1 PLANT PROMOTER Syngenta Limited (GB) 2001-08-08 EP claimed
WO-2000018930-A1 PLANT PROMOTER SYNGENTA LIMITED (GB) 2000-04-06 WO claimed
US-20210241846-A1 MULTICELLULAR METABOLIC MODELS AND METHODS GENOMATICA INC (US) 2021-08-05 US disclosed
US-20150302141-A1 MULTICELLULAR METABOLIC MODELS AND METHODS GENOMATICA INC (US) 2015-10-22 US disclosed
US-8949032-B2 Multicellular metabolic models and methods GENOMATICA, INC. (US) 2015-02-03 US disclosed
US-20060147899-A1 Multicellular metabolic models and methods GENOMATICA, INC. 2006-07-06 US disclosed
US-6700039-B1 USE OF TARGET AND ORGAN SPECIFIC PROMOTERS CONTROLLING EXPRESSION OF DNA SEQUENCES INHIBITING SPROUTING IN PLANT VEGETATIVE STORAGE ORGANS (E.G., POTATO TUBERS) RESULTING IN INCREASED LONG TERM STORAGE AND MINIMAL LOSS IN FOOD QUALITY SYNGENTA LIMITED (GB) 2004-03-02 US disclosed
EP-1121443-A1 PLANT PROMOTER Syngenta Limited (GB) 2001-08-08 EP disclosed
EP-1017830-A1 GENETIC METHOD FOR CONTROLLING SPROUTING ZENECA LIMITED (GB) 2000-07-12 EP disclosed
WO-2000018930-A1 PLANT PROMOTER SYNGENTA LIMITED (GB) 2000-04-06 WO disclosed
WO-1999006578-A2 GENETIC METHOD FOR CONTROLLING SPROUTING ZENECA LIMITED (GB) 1999-02-11 WO disclosed