Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 1/20 | 0.33 |
| ▸ | CTSK | P43235 | 1/20 | 0.33 |
| ▸ | BACE1 | P56817 | 1/20 | 0.32 |
| ▸ | TDP2 | O95551 | 2/20 | 0.30 |
| ▸ | BCL2 | P10415 | 1/20 | 0.30 |
| ▸ | HTR7 | P34969 | 1/20 | 0.30 |
| ▸ | MMP12 | P39900 | 1/20 | 0.30 |
| ▸ | MMP13 | P45452 | 1/20 | 0.30 |
| ▸ | HTR1A | P08908 | 1/20 | 0.30 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.30 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.30 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.30 |
| ▸ | DRD4 | P21917 | 1/20 | 0.30 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.30 |
| ▸ | HTR2C | P28335 | 1/20 | 0.30 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.30 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.30 |
| ▸ | HTR2B | P41595 | 1/20 | 0.30 |
| ▸ | HTR5A | P47898 | 1/20 | 0.30 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2052254 | 0.93 | MPL (0.33) | SLC6A2HTR2CSLC6A4 | |
| SCHEMBL2047276 | 0.90 | BCL2 (0.40) | BACE1TDP2BCL2HTR1AADRA2A | |
| SCHEMBL2045017 | 0.86 | MMP12 (0.36) | MMP12MMP13 | |
| SCHEMBL2047309 | 0.80 | PARP10 (0.44) | TDP2SIGMAR1 | |
| SCHEMBL2048603 | 0.79 | MPL (0.41) | MMP12MMP13 | |
| SCHEMBL2051196 | 0.78 | HDAC4 (0.35) | TDP2 | |
| SCHEMBL2051839 | 0.78 | PTK2 (0.33) | TDP2MMP12MMP13 | |
| SCHEMBL2051675 | 0.77 | KIF11 (0.40) | TDP2TMEM97SIGMAR1 | |
| SCHEMBL717055 | 0.77 | TDP2 (0.46) | TDP2MMP12MMP13 | |
| SCHEMBL1902719 | 0.76 | DRD2 (0.40) | MMP12MMP13SLC6A2HTR2CSLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110152463-A1 | RESIN COMPOSITION | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2011-06-23 | — | — | US | disclosed |