Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 3/20 | 0.46 |
| ▸ | CA1 | P00915 | 3/20 | 0.46 |
| ▸ | CA2 | P00918 | 3/20 | 0.46 |
| ▸ | CA9 | Q16790 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | CASP3 | P42574 | 1/20 | 0.45 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.45 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.45 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.45 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.44 |
| ▸ | KDR | P35968 | 9/20 | 0.43 |
| ▸ | LCK | P06239 | 2/20 | 0.43 |
| ▸ | CSF1R | P07333 | 2/20 | 0.43 |
| ▸ | LYN | P07948 | 2/20 | 0.43 |
| ▸ | FLT1 | P17948 | 2/20 | 0.43 |
| ▸ | FLT4 | P35916 | 2/20 | 0.43 |
| ▸ | FLT3 | P36888 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20500986 | 0.84 | MEN1 (0.54) | CA12CA1CA2CA9MEN1 | |
| SCHEMBL20500971 | 0.79 | SLC2A1 (0.52) | CA2CA9MEN1KMT2ANPC1 | |
| SCHEMBL24176904 | 0.79 | RAB9A (0.49) | CA2MEN1KMT2ANPC1RAB9A | |
| SCHEMBL20501022 | 0.78 | SCN9A (0.50) | MEN1KMT2ANPC1RAB9ACASP3 | |
| SCHEMBL13655214 | 0.78 | SCN9A (0.54) | NPC1RAB9ATRPV1S1PR4S1PR1 | |
| SCHEMBL20501151 | 0.78 | SCN4A (0.44) | CA12CA1CA2CA9MEN1 | |
| SCHEMBL20501046 | 0.76 | KDR (0.44) | KDRLCKCSF1RLYNFLT1 | |
| SCHEMBL20501048 | 0.74 | SCN9A (0.64) | RAB9AKDRROCK2PDGFRBMAPT | |
| SCHEMBL20501115 | 0.74 | SCN9A (0.52) | MEN1KMT2ANPC1RAB9AKDR | |
| SCHEMBL24176655 | 0.73 | SCN4A (0.49) | MEN1KMT2ANPC1RAB9AKDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11582970-B2 | 2-aminoimidazole-phenyl derivatives useful for controlling microbial growth | NORTH CAROLINA STATE UNIVERSITY (US) | 2023-02-21 | — | — | US | disclosed |
| US-20220000118-A1 | 2-AMINOIMIDAZOLE-PHENYL DERIVATIVES USEFUL FOR CONTROLLING MICROBIAL GROWTH | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2022-01-06 | — | — | US | disclosed |
| CN-110740645-A | 2-aminoimidazole-phenyl derivatives for controlling microbial growth | 北卡罗莱纳州立大学 | 2020-01-31 | — | — | CN | disclosed |
| WO-2018169752-A1 | 2-AMINOIMIDAZOLE-PHENYL DERIVATIVES USEFUL FOR CONTROLLING MICROBIAL GROWTH | NORTH CAROLINA STATE UNIVERSITY (US) | 2018-09-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11582970-B2 | 2-aminoimidazole-phenyl derivatives useful for controlling microbial growth | DDC, IL4I1, ING2 | CA12 4757/4885CA1 4750/4885CA2 1994/4885 |
| US-20220000118-A1 | 2-AMINOIMIDAZOLE-PHENYL DERIVATIVES USEFUL FOR CONTROLLING MICROBIAL GROWTH | DDC, IL4I1, ING2 | CA12 4757/4885CA1 4750/4885CA2 1994/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.