Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 2/20 | 0.31 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2050169 | 0.85 | POLB (0.35) | HDAC1HDAC2LMNA | |
| SCHEMBL5133715 | 0.79 | LMNA (0.36) | HDAC1HDAC2LMNA | |
| SCHEMBL18084525 | 0.79 | EHMT2 (0.36) | LMNA | |
| SCHEMBL18726574 | 0.79 | HDAC1 (0.37) | HDAC1HDAC2LMNA | |
| SCHEMBL574827 | 0.79 | HDAC1 (0.37) | HDAC1HDAC2LMNA | |
| SCHEMBL29353376 | 0.79 | HDAC1 (0.37) | HDAC1HDAC2LMNA | |
| SCHEMBL1746858 | 0.78 | ALDH1A1 (0.35) | LMNA | |
| SCHEMBL18726765 | 0.77 | HDAC1 (0.40) | HDAC1HDAC2LMNA | |
| SCHEMBL7201002 | 0.74 | POLB (0.32) | LMNA | |
| SCHEMBL9904994 | 0.73 | HDAC1 (0.36) | HDAC1HDAC2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8846080-B2 | Vaccine | GLAXOSMITHKLINE BIOLOGICALS S.A. (BE) | 2014-09-30 | — | — | US | disclosed |
| US-20110159081-A1 | VACCINE | GLAXOSMITHKLINE BIOLOGICALS S.A. | 2011-06-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110159081-A1 | VACCINE | LY96, CD47, CD74 | HDAC1 2639/4885HDAC2 2838/4885LMNA 2746/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.