Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | METAP2 | P50579 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29164212 | 0.83 | KMT2A (0.38) | ALDH1A1PKMLMNAKMT2AMEN1 | |
| SCHEMBL1888896 | 0.79 | ALDH1A1 (0.37) | POLBALDH1A1PKMLMNAKMT2A | |
| SCHEMBL1746858 | 0.78 | ALDH1A1 (0.35) | POLBALDH1A1LMNAKMT2AMEN1 | |
| SCHEMBL8328957 | 0.77 | ALDH1A1 (0.39) | POLBALDH1A1LMNAKMT2AMEN1 | |
| SCHEMBL5133715 | 0.75 | LMNA (0.36) | POLBALDH1A1PKMLMNAKMT2A | |
| SCHEMBL342420 | 0.74 | POLB (0.45) | POLBALDH1A1PKMKMT2AMEN1 | |
| SCHEMBL2050166 | 0.74 | HDAC1 (0.31) | LMNA | |
| SCHEMBL15698867 | 0.72 | ALDH1A1 (0.32) | ALDH1A1LMNAKMT2AMEN1NPC1 | |
| SCHEMBL12092095 | 0.71 | LMNA (0.42) | POLBALDH1A1PKMLMNAKMT2A | |
| SCHEMBL43414 | 0.71 | POLB (0.41) | POLBALDH1A1PKMLMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003104424-A2 | NOVEL MOLECULAR CONJUGATES FOR SIGNAL AMPLIFICATION | THE GOVERNMENT OF THE UNITED STATES, AS REPRESENTED BY THE SECRETARY OF THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2003-12-18 | — | — | WO | disclosed |