Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | SNCA | P37840 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.35 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.35 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4957637 | 0.83 | MAPT (0.44) | MEN1KMT2AALDH1A1L3MBTL1NPC1 | |
| SCHEMBL3228023 | 0.80 | CNR2 (0.43) | MEN1KMT2AALDH1A1L3MBTL1NPC1 | |
| SCHEMBL2050997 | 0.79 | CYSLTR1 (0.53) | MEN1KMT2AABCG2CYSLTR2CYSLTR1 | |
| SCHEMBL1882737 | 0.77 | CYP3A4 (0.53) | MEN1KMT2ACYP3A4SNCAALDH1A1 | |
| SCHEMBL9335553 | 0.76 | UNG (0.41) | MEN1KMT2AALDH1A1NPC1MAPT | |
| SCHEMBL16372021 | 0.75 | CYP3A4 (0.61) | MEN1KMT2ACYP3A4SNCAALDH1A1 | |
| SCHEMBL157805 | 0.75 | CYP3A4 (0.61) | MEN1KMT2ACYP3A4SNCAALDH1A1 | |
| SCHEMBL9757049 | 0.75 | NR4A2 (0.41) | MEN1KMT2AALDH1A1MAPTCNR2 | |
| SCHEMBL9756946 | 0.74 | CYSLTR2 (0.45) | MEN1KMT2ACYP3A4ALDH1A1L3MBTL1 | |
| SCHEMBL9335423 | 0.74 | PRSS1 (0.38) | NPC1MAPTHTTRAB9ACNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008035379-A2 | PROCESS FOR AND INTERMEDIATES OF LEUKOTRIENE ANTAGONISTS | APTUIT LAURUS PRIVATE LIMITED (IN) | 2008-03-27 | — | — | WO | claimed |
| WO-2009001374-A3 | PREPARATION OF ETHYL-3'-[((7-CHLORO-2-QUINOLINYL)ETHENYL)PHENYL]-3-OXOPROPANOATE, A KEY INTERMEDIATE FOR MONTELUKAST SODIUM | APTUIT LAURUS PVT LTD (IN) | 2011-06-30 | — | — | WO | disclosed |
| WO-2008035379-A3 | PROCESS FOR AND INTERMEDIATES OF LEUKOTRIENE ANTAGONISTS | APTUIT LAURUS PRIVATE LIMITED (IN) | 2010-02-18 | — | — | WO | disclosed |
| WO-2009001374-A2 | PREPARATION OF ETHYL-3'-[((7-CHLORO-2-QUINOLINYL)ETHENYL)PHENYL]-3-OXOPROPANOATE, A KEY INTERMEDIATE FOR MONTELUKAST SODIUM | APTUIT LAURUS PVT LTD (IN) | 2008-12-31 | — | — | WO | disclosed |
| WO-2008035379-A2 | PROCESS FOR AND INTERMEDIATES OF LEUKOTRIENE ANTAGONISTS | APTUIT LAURUS PRIVATE LIMITED (IN) | 2008-03-27 | — | — | WO | disclosed |
| WO-2008035379-A2 | PROCESS FOR AND INTERMEDIATES OF LEUKOTRIENE ANTAGONISTS | APTUIT LAURUS PRIVATE LIMITED (IN) | 2008-03-27 | — | — | WO | disclosed |