Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UNG | P13051 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.40 |
| ▸ | GAA | P10253 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | CNR2 | P34972 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | CYSLTR2 | Q9NS75 | 6/20 | 0.36 |
| ▸ | CYSLTR1 | Q9Y271 | 6/20 | 0.36 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.35 |
| ▸ | CBLB | Q13191 | 1/20 | 0.34 |
| ▸ | AR | P10275 | 1/20 | 0.33 |
| ▸ | TERT | O14746 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9335143 | 0.85 | CNR2 (0.48) | UNGMAPTSMN1; SMN2GAAKMT2A | |
| SCHEMBL3228023 | 0.82 | CNR2 (0.43) | MAPTSMN1; SMN2GAAKMT2AKDM4E | |
| SCHEMBL9757049 | 0.81 | NR4A2 (0.41) | MAPTSMN1; SMN2GAAKMT2AKDM4E | |
| SCHEMBL9335203 | 0.79 | UNG (0.40) | UNGMAPTSMN1; SMN2KMT2AKDM4E | |
| SCHEMBL9335423 | 0.78 | PRSS1 (0.38) | MAPTSMN1; SMN2CNR2NPC1RAB9A | |
| SCHEMBL4957637 | 0.78 | MAPT (0.44) | MAPTGAAKMT2AMEN1ALDH1A1 | |
| SCHEMBL9338917 | 0.77 | SMN1; SMN2 (0.44) | UNGMAPTSMN1; SMN2GAAKMT2A | |
| SCHEMBL9339015 | 0.76 | CBLB (0.41) | CNR2CYSLTR2CYSLTR1NR4A2CBLB | |
| SCHEMBL9756946 | 0.76 | CYSLTR2 (0.45) | MAPTSMN1; SMN2KMT2AKDM4EMEN1 | |
| SCHEMBL2050999 | 0.76 | MEN1 (0.39) | MAPTSMN1; SMN2GAAKMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0533695-B1 | IMIDAZO (4,5-c) PYRIDINES WITH PAF ANTAGONIST ACTIVITY | PFIZER (US) | 1994-10-05 | — | — | EP | disclosed |
| US-5322847-A | Inhibit platelet activating factor, block leukotriene D4 receptors | PFIZER INC. (US) | 1994-06-21 | — | — | US | disclosed |
| EP-0533695-A1 | IMIDAZO (4,5-c) PYRIDINES WITH PAF ANTAGONIST ACTIVITY. | PFIZER (US) | 1993-03-31 | — | — | EP | disclosed |
| WO-1991017163-A1 | IMIDAZO (4,5-c) PYRIDINES WITH PAF ANTAGONIST ACTIVITY | PFIZER INC. (US) | 1991-11-14 | — | — | WO | disclosed |