Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 2/20 | 0.49 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.49 |
| ▸ | TP53 | P04637 | 3/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | APEX1 | P27695 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1930129 | 0.88 | ALDH1A1 (0.61) | ALDH1A1CYP3A4TP53ALOX15TSHR | |
| SCHEMBL28846374 | 0.87 | MEN1 (0.47) | EPHX2NR1H4MEN1NPC1RAB9A | |
| SCHEMBL7777160 | 0.81 | RELA (0.60) | ALDH1A1CYP3A4TP53ALOX15TSHR | |
| SCHEMBL3168388 | 0.81 | RELA (0.60) | ALDH1A1CYP3A4TP53ALOX15TSHR | |
| SCHEMBL5360664 | 0.79 | NFE2L2 (0.61) | MEN1KMT2AL3MBTL1ALDH1A1CYP3A4 | |
| SCHEMBL5507847 | 0.79 | ALDH1A1 (0.52) | MEN1NPC1RAB9AKMT2AALDH1A1 | |
| SCHEMBL5253949 | 0.79 | ALDH1A1 (0.52) | MEN1NPC1RAB9AKMT2AALDH1A1 | |
| SCHEMBL8749818 | 0.79 | CALM1 (0.58) | MEN1NPC1RAB9AKMT2AALDH1A1 | |
| SCHEMBL16225102 | 0.79 | LMNA (0.44) | EPHX2NR1H4MEN1NPC1RAB9A | |
| SCHEMBL6680147 | 0.79 | ALDH1A1 (0.52) | MEN1NPC1RAB9AKMT2AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2510118-A2 | PREFERENTIAL AMPLIFICATION OF MRNA OVER DNA USING CHEMICALLY MODIFIED PRIMERS | Roche Diagniostics GmbH (DE) | 2012-10-17 | — | — | EP | disclosed |
| WO-2011069676-A2 | PREFERENTIAL AMPLIFICATION OF MRNA OVER DNA USING CHEMICALLY MODIFIED PRIMERS | ROCHE DIAGNOSTICS GMBH (DE) | 2011-06-16 | — | — | WO | disclosed |