Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20515340 | 0.72 | FAAH (0.47) | LMNA | |
| SCHEMBL31621867 | 0.72 | MAOA (0.42) | LMNA | |
| SCHEMBL29198044 | 0.71 | KDM4E (0.34) | LMNA | |
| SCHEMBL7813478 | 0.70 | S1PR4 (0.45) | HRH3PDE10A | |
| SCHEMBL29645129 | 0.66 | PDE10A (0.45) | HRH3PDE10A | |
| SCHEMBL31621869 | 0.65 | MEN1 (0.44) | — | |
| SCHEMBL22352992 | 0.65 | PSMB5 (0.40) | HRH3 | |
| SCHEMBL31621849 | 0.65 | LMNA (0.49) | LMNA | |
| SCHEMBL31621848 | 0.64 | IDO1 (0.40) | LMNA | |
| SCHEMBL3972257 | 0.63 | HRH3 (0.46) | HRH3PDE10ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180282280-A1 | QUINOLINE-BASED PROTEASOME INHIBITORS AND USES THEREOF | NATIONAL SCIENCE FOUNDATION | 2018-10-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180282280-A1 | QUINOLINE-BASED PROTEASOME INHIBITORS AND USES THEREOF | PSME1, PSMB1, PSME3 | HRH3 2502/4885PDE10A 4232/4885LMNA 3116/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.