Sugi Predict

Sugi Predict / Compounds / SCHEMBL20520537

SCHEMBL20520537

SCHEMBL20520537

O=C(CO)c1cnc(Cl)s1

nearest known ligand 0.47

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
▸ SMN1; SMN2 Q16637 3/20 0.37
▸ ALDH1A1 P00352 4/20 0.36
▸ LMNA P02545 3/20 0.36
▸ KDM4E B2RXH2 2/20 0.36
▸ L3MBTL1 Q9Y468 4/20 0.35
▸ ALOX12 P18054 1/20 0.35
▸ HCAR2 Q8TDS4 1/20 0.34
▸ KMT2A Q03164 3/20 0.34
▸ MAPT P10636 3/20 0.34
▸ MEN1 O00255 2/20 0.34
▸ NPC1 O15118 1/20 0.34
▸ RAB9A P51151 1/20 0.34
▸ GSK3B P49841 1/20 0.33
▸ IDO1 P14902 1/20 0.33
▸ TDO2 P48775 1/20 0.33
▸ CYP1A2 P05177 1/20 0.33
▸ CYP2C9 P11712 1/20 0.33
▸ CYP2C19 P33261 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20520649 0.84 GSK3B (0.50) SMN1; SMN2ALDH1A1LMNAMAPTNPC1
SCHEMBL21853882 0.82 ALDH1A1 (0.38) SMN1; SMN2ALDH1A1LMNAKDM4EL3MBTL1
SCHEMBL21862393 0.82 SMN1; SMN2 (0.36) SMN1; SMN2ALDH1A1LMNAKDM4EL3MBTL1
SCHEMBL293931 0.77 — —
SCHEMBL3052942 0.77 — —
SCHEMBL23959903 0.77 FAAH (0.40) SMN1; SMN2ALDH1A1LMNAL3MBTL1NPC1
SCHEMBL21858161 0.76 ALDH1A1 (0.33) SMN1; SMN2ALDH1A1LMNAL3MBTL1KMT2A
SCHEMBL20520527 0.75 ALDH1A1 (0.41) SMN1; SMN2ALDH1A1LMNAKDM4EL3MBTL1
SCHEMBL21841051 0.75 FAAH (0.42) L3MBTL1NPC1
SCHEMBL4966007 0.75 — —

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12144349-B2 Pesticidal mixtures comprising a mesoionic compound BASF SE (DE) 2024-11-19 — — US disclosed
US-20230159562-A1 PYRIMIDINIUM COMPOUNDS AND THEIR MIXTURES FOR COMBATING ANIMAL PESTS BASF SE (DE) 2023-05-25 — — US disclosed
CN-116102580-A Pyrimidinium compounds and mixtures thereof for combating animal pests 巴斯夫欧洲公司 2023-05-12 — — CN disclosed
CN-116082366-A Pyrimidinium compounds and mixtures thereof for combating animal pests 巴斯夫欧洲公司 2023-05-09 — — CN disclosed
CN-116076518-A Pyrimidinium compounds and mixtures thereof for combating animal pests 巴斯夫欧洲公司 2023-05-09 — — CN disclosed
US-11578083-B2 Pyrimidinium compounds and their mixtures for combating animal pests BASF SE (DE) 2023-02-14 — — US disclosed
EP-3978504-A1 CHIRAL 2,3-DIHYDROTHIAZOLO[3,2-A]PYRIMIDINE DERIVATIVES FOR COMBATING ANIMAL PESTS BASF SE (DE) 2022-04-06 — — EP disclosed
US-20220046924-A1 METHOD FOR CONTROLLING PESTS OF POTATO PLANTS BASF SE (DE) 2022-02-17 — — US disclosed
US-20210368794-A1 PESTICIDAL MIXTURES COMPRISING A MESOIONIC COMPOUND BASF SE (DE) 2021-12-02 — — US disclosed
US-20210368794-A1 PESTICIDAL MIXTURES COMPRISING A MESOIONIC COMPOUND BASF SE (DE) 2021-12-02 — — US disclosed
WO-2020064501-A1 METHOD FOR CONTROLLING PESTS OF CITRUS PLANTS BASF SE (DE) 2020-04-02 — — WO disclosed
EP-3628157-A1 METHOD OF CONTROLLING INSECTICIDE RESISTANT INSECTS AND VIRUS TRANSMISSION TO PLANTS BASF SE (DE) 2020-04-01 — — EP disclosed
EP-3628158-A1 PESTICIDAL MIXTURE COMPRISING A MESOIONIC COMPOUND AND A BIOPESTICIDE BASF SE (DE) 2020-04-01 — — EP disclosed
EP-3628156-A1 METHOD FOR CONTROLLING PESTS OF SUGARCANE, CITRUS, RAPESEED, AND POTATO PLANTS BASF SE (DE) 2020-04-01 — — EP disclosed
WO-2020058010-A1 PESTICIDAL MIXTURES COMPRISING A MESOIONIC COMPOUND BASF SE (DE) 2020-03-26 — — WO disclosed
WO-2020058010-A1 PESTICIDAL MIXTURES COMPRISING A MESOIONIC COMPOUND BASF SE (DE) 2020-03-26 — — WO disclosed
EP-3619217-A1 PROCESS FOR PREPARING CHIRAL 2,3-DIHYDROTHIAZOLO[3,2-A]PYRIMIDIN-4-IUM COMPOUNDS BASF SE (DE) 2020-03-11 — — EP disclosed
EP-3601298-A1 PROCESS FOR PREPARING CHIRAL 2,3-DIHYDROTHIAZOLO[3,2-A]PYRIMIDIN-4-IUM COMPOUNDS BASF SE (DE) 2020-02-05 — — EP disclosed
WO-2018202654-A1 PROCESS FOR PREPARING CHIRAL 2,3-DIHYDROTHIAZOLO[3,2-A]PYRIMIDIN-4-IUM COMPOUNDS BASF SE (DE) 2018-11-08 — — WO disclosed
WO-2018177970-A1 PROCESS FOR PREPARING CHIRAL 2,3-DIHYDROTHIAZOLO[3,2-A]PYRIMIDIN-4-IUM COMPOUNDS BASF SE (DE) 2018-10-04 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230159562-A1 PYRIMIDINIUM COMPOUNDS AND THEIR MIXTURES FOR COMBATING ANIMAL PESTS THOP1, NIT2, DDT SMN1; SMN2 1231/4885ALDH1A1 1463/4885LMNA 3730/4885
US-11578083-B2 Pyrimidinium compounds and their mixtures for combating animal pests THOP1, NIT2, DDT SMN1; SMN2 1316/4885ALDH1A1 1846/4885LMNA 3592/4885
US-12144349-B2 Pesticidal mixtures comprising a mesoionic compound ACHE, DDT, MTX2 SMN1; SMN2 386/4885ALDH1A1 2413/4885LMNA 2292/4885
US-20220046924-A1 METHOD FOR CONTROLLING PESTS OF POTATO PLANTS STOM, DDT, PIR SMN1; SMN2 2598/4885ALDH1A1 4346/4885LMNA 2493/4885
US-20210368794-A1 PESTICIDAL MIXTURES COMPRISING A MESOIONIC COMPOUND ACHE, DDT, MTX2 SMN1; SMN2 386/4885ALDH1A1 2413/4885LMNA 2292/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.