SCHEMBL20521982

SCHEMBL20521982

C1=CC(=C(CCCc2ccccc2)c2ccccc2)C=C1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 2/20 0.53
NPC1 O15118 2/20 0.53
RAB9A P51151 2/20 0.53
CASP3 P42574 1/20 0.53
SENP8 Q96LD8 1/20 0.53
SENP7 Q9BQF6 1/20 0.53
SENP6 Q9GZR1 1/20 0.53
HDAC1 Q13547 4/20 0.48
HDAC3 O15379 3/20 0.48
HDAC2 Q92769 3/20 0.48
HDAC8 Q9BY41 3/20 0.48
HDAC6 Q9UBN7 3/20 0.48
HDAC5 Q9UQL6 3/20 0.48
HDAC4 P56524 2/20 0.48
HDAC7 Q8WUI4 2/20 0.48
HDAC10 Q969S8 2/20 0.48
HDAC11 Q96DB2 2/20 0.48
HDAC9 Q9UKV0 2/20 0.48
MAPK1 P28482 1/20 0.48
ADRA1A P35348 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16411369 0.77 CES1 (0.41) HDAC8HDAC6MAPK1KMT2AMAPT
SCHEMBL20521131 0.75 MAPT (0.38) TDP1HDAC1HDAC3HDAC2HDAC8
SCHEMBL28580453 0.72 HDAC1 (0.43) TDP1NPC1RAB9ACASP3SENP8
SCHEMBL4389892 0.71 AKT1 (0.34) MAPK1MAPT
SCHEMBL9303827 0.71 ATM (0.43) TDP1RAB9AHDAC1HDAC3HDAC2
SCHEMBL839278 0.69 TDP1 (1.00) TDP1NPC1RAB9ACASP3SENP8
SCHEMBL5012485 0.69 TDP1 (0.60) TDP1NPC1RAB9ACASP3SENP8
SCHEMBL10336435 0.69 TDP1 (0.60) TDP1NPC1RAB9ACASP3SENP8
SCHEMBL16411470 0.68 L3MBTL1 (0.56) TDP1NPC1RAB9AKMT2AMAPT
SCHEMBL647841 0.67 TDP1 (0.40) TDP1NPC1RAB9AHDAC6MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-121574291-A Borate activated metallocene catalysts 博里利斯股份公司 2026-02-27 CN disclosed
EP-3601385-B1 BORATE-ACTIVATED METALLOCENE CATALYSTS BOREALIS AG (AT) 2023-05-03 EP disclosed
US-11192963-B2 Borate-activated metallocene catalysts BOREALIS AG (AT) 2021-12-07 US disclosed
US-11192963-B2 Borate-activated metallocene catalysts BOREALIS AG (AT) 2021-12-07 US disclosed
US-20210108006-A1 BORATE-ACTIVATED METALLOCENE CATALYSTS BOREALIS AG (AT) 2021-04-15 US disclosed
US-20210108006-A1 BORATE-ACTIVATED METALLOCENE CATALYSTS BOREALIS AG (AT) 2021-04-15 US disclosed
EP-3601385-A1 BORATE-ACTIVATED METALLOCENE CATALYSTS Borealis AG (AT) 2020-02-05 EP disclosed
CN-110475793-A The metallocene catalyst of borate activatable BOREALIS AG 2019-11-19 CN disclosed
WO-2018178152-A1 BORATE-ACTIVATED METALLOCENE CATALYSTS BOREALIS AG (AT) 2018-10-04 WO disclosed