Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.60 |
| ▸ | NPC1 | O15118 | 2/20 | 0.60 |
| ▸ | RAB9A | P51151 | 2/20 | 0.60 |
| ▸ | CASP3 | P42574 | 1/20 | 0.60 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.60 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.60 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.60 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.55 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.55 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.55 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.55 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.55 |
| ▸ | HDAC5 | Q9UQL6 | 3/20 | 0.55 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.55 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.55 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.55 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.55 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1305408 | 0.87 | ALDH1A1 (0.59) | TDP1NPC1RAB9ACASP3SENP8 | |
| SCHEMBL3281895 | 0.84 | L3MBTL1 (0.44) | TDP1NPC1RAB9ACASP3SENP8 | |
| SCHEMBL1478009 | 0.80 | HDAC1 (0.61) | TDP1NPC1RAB9ACASP3SENP8 | |
| SCHEMBL3298136 | 0.79 | CES1 (0.46) | TDP1MAPK1SMN1; SMN2ALDH1A1HSD17B10 | |
| SCHEMBL820442 | 0.78 | PTGS2 (0.59) | ALDH1A1KMT2ATRPV1 | |
| SCHEMBL2163834 | 0.78 | HDAC1 (0.59) | TDP1NPC1RAB9ACASP3SENP8 | |
| SCHEMBL9753129 | 0.77 | THRA (0.56) | SLC6A3ALDH1A1HSD17B10MAPTKMT2A | |
| SCHEMBL110777 | 0.77 | ALDH1A1 (0.76) | TDP1NPC1RAB9ACASP3SENP8 | |
| SCHEMBL816636 | 0.77 | CES2 (0.58) | TDP1ALDH1A1MAPT | |
| SCHEMBL11782089 | 0.77 | HDAC1 (0.57) | TDP1NPC1RAB9ACASP3SENP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080207864-A1 | Organosilanes, Process For Production of the Same, and Use Thereof | SHARP KABUSHIKI KAISHA (JP) | 2008-08-28 | — | — | US | disclosed |
| EP-0744392-A1 | A new one-pot process for the preparation of 7-aryl-2,6-disubstituted quinone methides | CIBA-GEIGY AG (CH) | 1996-11-27 | — | — | EP | disclosed |
| US-4973585-A | INHIBITORS OF ANGIOTENSIN CONVERTING ENZYME | MERRELL DOW PHARMACEUTICALS (US) | 1990-11-27 | — | — | US | disclosed |