SCHEMBL20522364

SCHEMBL20522364

CC(=O)Nc1ncc(C2CCN(S(=O)(=O)c3ccc(F)cc3)CC2)s1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ KMT2A Q03164 3/20 0.54
▸ MEN1 O00255 2/20 0.54
▸ LMNA P02545 2/20 0.50
▸ TSHR P16473 1/20 0.50
▸ MAPK10 P53779 1/20 0.50
▸ HSD17B10 Q99714 1/20 0.50
▸ ATM Q13315 1/20 0.48
▸ OGA O60502 2/20 0.47
▸ SMN1; SMN2 Q16637 1/20 0.47
▸ HDAC3 O15379 1/20 0.47
▸ HDAC4 P56524 1/20 0.47
▸ HDAC1 Q13547 1/20 0.47
▸ HDAC7 Q8WUI4 1/20 0.47
▸ HDAC2 Q92769 1/20 0.47
▸ HDAC10 Q969S8 1/20 0.47
▸ HDAC11 Q96DB2 1/20 0.47
▸ HDAC8 Q9BY41 1/20 0.47
▸ HDAC6 Q9UBN7 1/20 0.47
▸ HDAC9 Q9UKV0 1/20 0.47
▸ HDAC5 Q9UQL6 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20522305 0.78 HTR2B (0.52) KMT2AMEN1LMNAHDAC3HDAC4
SCHEMBL13521311 0.75 CCNE1 (0.46) OGASMN1; SMN2
SCHEMBL28531250 0.74 KMT2A (0.67) KMT2AMEN1LMNAATMSMN1; SMN2
SCHEMBL5782986 0.73 CCNE1 (0.60) KMT2AMEN1LMNATSHRHSD17B10
SCHEMBL20883053 0.72 CCNE1 (0.60) OGASMN1; SMN2RAB9A
SCHEMBL16113250 0.70 OGA (0.73) OGASMN1; SMN2HTT
SCHEMBL20522416 0.70 CCNE1 (0.48) SMN1; SMN2
Hydrochloric Acid SCHEMBL27035859 0.69 CCNE1 (0.47) SMN1; SMN2
SCHEMBL20522288 0.69 GPR119 (0.51) MAPT
SCHEMBL28224185 0.68 ALDH1A1 (0.66) KMT2AMEN1TP53L3MBTL1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260001873-A1 NOVEL INHIBITORS VIVORYON THERAPEUTICS N.V. (DE) 2026-01-01 — — US disclosed
US-12384772-B2 Inhibitors VIVORYON THERAPEUTICS N.V. (DE) 2025-08-12 — — US disclosed
CN-117024352-A Novel inhibitors 维沃里翁治疗股份有限公司 2023-11-10 — — CN disclosed
CN-110719910-B Novel inhibitors 维沃里翁治疗股份有限公司 2023-07-21 — — CN disclosed
US-20220274977-A1 NOVEL INHIBITORS VIVORYON THERAPEUTICS N.V. (DE) 2022-09-01 — — US disclosed
US-11339152-B2 Inhibitors VIVORYON THERAPEUTICS N.V. 2022-05-24 — — US disclosed
US-11339152-B2 Inhibitors VIVORYON THERAPEUTICS N.V. 2022-05-24 — — US disclosed
US-20200377493-A1 NOVEL INHIBITORS VIVORYON THERAPEUTICS N.V. (DE) 2020-12-03 — — US disclosed
US-20200377493-A1 NOVEL INHIBITORS VIVORYON THERAPEUTICS N.V. (DE) 2020-12-03 — — US disclosed
EP-3601269-A1 NOVEL INHIBITORS Probiodrug AG (DE) 2020-02-05 — — EP disclosed
CN-110719910-A Novel inhibitors 前体生物药物股份公司 2020-01-21 — — CN disclosed
WO-2018178384-A1 NOVEL INHIBITORS PROBIODRUG AG (DE) 2018-10-04 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260001873-A1 NOVEL INHIBITORS GLS, GLS2, SULT1E1 KMT2A 3101/4885MEN1 3715/4885LMNA 3585/4885
US-20200377493-A1 NOVEL INHIBITORS GLUL, GLS, QPCT KMT2A 2829/4885MEN1 4443/4885LMNA 3291/4885
US-11339152-B2 Inhibitors GLUL, QPCT, GLS KMT2A 2908/4885MEN1 4170/4885LMNA 3155/4885
US-12384772-B2 Inhibitors GLS, QPCT, GLS2 KMT2A 2772/4885MEN1 4216/4885LMNA 3549/4885
US-20220274977-A1 NOVEL INHIBITORS GLUL, GLS, QPCT KMT2A 2867/4885MEN1 4169/4885LMNA 3650/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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