Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | PDE4A | P27815 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20522273 | 0.83 | ALDH1A1 (0.53) | ALDH1A1KDM4EHSD17B10TDP1CYP3A4 | |
| SCHEMBL2936122 | 0.81 | ALDH1A1 (0.47) | ALDH1A1KDM4EHSD17B10TDP1CYP3A4 | |
| SCHEMBL25577619 | 0.78 | PAX8 (0.50) | TDP1PTGS2MEN1KMT2A | |
| SCHEMBL2498725 | 0.75 | ALOX5AP (0.44) | CYP3A4PTGS2PTGS1 | |
| SCHEMBL11292098 | 0.75 | KDM4E (0.54) | ALDH1A1KDM4EHSD17B10TDP1CYP3A4 | |
| SCHEMBL1336741 | 0.73 | ALDH1A1 (0.52) | ALDH1A1KDM4EHSD17B10TDP1CYP3A4 | |
| SCHEMBL17850711 | 0.73 | L3MBTL1 (0.43) | ALDH1A1PTGS2PTGS1 | |
| SCHEMBL29788143 | 0.73 | ERN1 (0.54) | ALDH1A1KDM4EHSD17B10TSHRPTGS2 | |
| SCHEMBL30610422 | 0.73 | KIT (0.61) | ALDH1A1KDM4EHSD17B10TDP1CYP3A4 | |
| SCHEMBL11282919 | 0.73 | KDM4E (0.51) | ALDH1A1KDM4EHSD17B10TSHRCA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260001873-A1 | NOVEL INHIBITORS | VIVORYON THERAPEUTICS N.V. (DE) | 2026-01-01 | — | — | US | disclosed |
| US-12384772-B2 | Inhibitors | VIVORYON THERAPEUTICS N.V. (DE) | 2025-08-12 | — | — | US | disclosed |
| CN-117024352-A | Novel inhibitors | 维沃里翁治疗股份有限公司 | 2023-11-10 | — | — | CN | disclosed |
| CN-110719910-B | Novel inhibitors | 维沃里翁治疗股份有限公司 | 2023-07-21 | — | — | CN | disclosed |
| US-20220274977-A1 | NOVEL INHIBITORS | VIVORYON THERAPEUTICS N.V. (DE) | 2022-09-01 | — | — | US | disclosed |
| US-11339152-B2 | Inhibitors | VIVORYON THERAPEUTICS N.V. | 2022-05-24 | — | — | US | disclosed |
| US-20200377493-A1 | NOVEL INHIBITORS | VIVORYON THERAPEUTICS N.V. (DE) | 2020-12-03 | — | — | US | disclosed |
| EP-3601269-A1 | NOVEL INHIBITORS | Probiodrug AG (DE) | 2020-02-05 | — | — | EP | disclosed |
| CN-110719910-A | Novel inhibitors | 前体生物药物股份公司 | 2020-01-21 | — | — | CN | disclosed |
| WO-2018178384-A1 | NOVEL INHIBITORS | PROBIODRUG AG (DE) | 2018-10-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260001873-A1 | NOVEL INHIBITORS | GLS, GLS2, SULT1E1 | ALDH1A1 1183/4885KDM4E 1773/4885HSD17B10 786/4885 |
| US-20200377493-A1 | NOVEL INHIBITORS | GLUL, GLS, QPCT | ALDH1A1 1681/4885KDM4E 1119/4885HSD17B10 1015/4885 |
| US-11339152-B2 | Inhibitors | GLUL, QPCT, GLS | ALDH1A1 1490/4885KDM4E 1078/4885HSD17B10 963/4885 |
| US-12384772-B2 | Inhibitors | GLS, QPCT, GLS2 | ALDH1A1 1415/4885KDM4E 1254/4885HSD17B10 1103/4885 |
| US-20220274977-A1 | NOVEL INHIBITORS | GLUL, GLS, QPCT | ALDH1A1 1184/4885KDM4E 1160/4885HSD17B10 935/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.