SCHEMBL2052256

SCHEMBL2052256

CCCCc1cccc(-c2ccc3c(c2)[CH]c2cc(-c4cccc(CCCC)c4)ccc2-3)c1

nearest known ligand 0.44

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
LPL P06858 3/20 0.41
LIPG Q9Y5X9 3/20 0.41
PSMB5 P28074 1/20 0.40
HSD11B1 P28845 1/20 0.39
GPR3 P46089 1/20 0.37
SKP2 Q13309 1/20 0.37
BCL2 P10415 1/20 0.36
HTR7 P34969 1/20 0.36
XIAP P98170 1/20 0.36
NPC1 O15118 1/20 0.36
HPGD P15428 1/20 0.36
MAPK1 P28482 1/20 0.36
HTT P42858 1/20 0.36
RAB9A P51151 1/20 0.36
NPSR1 Q6W5P4 1/20 0.36
BCL2L2 Q92843 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2049240 0.90 CTSS (0.41) BCL2HTR7
SCHEMBL2048604 0.85 RARB (0.49) HSD11B1HPGD
SCHEMBL199210 0.84 LPL (0.52) LPLLIPGPSMB5HSD11B1SKP2
SCHEMBL2047278 0.83 BCL2 (0.51) BCL2NPC1MAPK1RAB9A
SCHEMBL2037494 0.81 SKP2 (0.48) PSMB5GPR3SKP2NPC1HPGD
SCHEMBL1902719 0.79 DRD2 (0.40) LPLLIPGPSMB5HSD11B1GPR3
SCHEMBL30500519 0.79 PSMB5 (0.49) LPLLIPGPSMB5HSD11B1BCL2
SCHEMBL11515483 0.79 PSMB5 (0.49) LPLLIPGPSMB5HSD11B1BCL2
SCHEMBL9658657 0.79 LPL (0.59) LPLLIPGHSD11B1
SCHEMBL28400225 0.78 HTR7 (0.53) LPLLIPGPSMB5HSD11B1GPR3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110152463-A1 RESIN COMPOSITION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-06-23 US disclosed