SCHEMBL2052786

SCHEMBL2052786

Clc1ccc2c(c1)-c1cc(Cl)ccc1[CH]2

nearest known ligand 0.46

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
S100A4 P26447 2/20 0.46
TSHR P16473 5/20 0.43
CYP3A4 P08684 4/20 0.43
ALDH1A1 P00352 3/20 0.43
ALOX15 P16050 2/20 0.43
SMN1; SMN2 Q16637 2/20 0.43
TDP1 Q9NUW8 2/20 0.43
TP53 P04637 2/20 0.42
PPOX P50336 1/20 0.41
CYP2A6 P11509 2/20 0.39
LMNA P02545 1/20 0.39
HSD17B10 Q99714 3/20 0.39
HPGD P15428 1/20 0.39
ALOX12 P18054 1/20 0.39
MAPK1 P28482 1/20 0.39
AHR P35869 2/20 0.37
TGM2 P21980 1/20 0.37
CES1 P23141 1/20 0.37
EPHX2 P34913 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2044633 0.77 S100A4 (0.46) S100A4TSHRCYP3A4ALDH1A1ALOX15
SCHEMBL14244621 0.72 PTPN11 (0.48) S100A4ALDH1A1ALOX15PPOXLMNA
SCHEMBL28607196 0.71 S100A4 (0.68) S100A4TSHRCYP3A4ALDH1A1ALOX15
SCHEMBL30839728 0.71 TSHR (0.65) S100A4TSHRCYP3A4ALDH1A1ALOX15
SCHEMBL11517368 0.71 TSHR (0.65) S100A4TSHRCYP3A4ALDH1A1ALOX15
SCHEMBL11377942 0.70 AHR (0.61) TSHRCYP3A4ALDH1A1ALOX15SMN1; SMN2
SCHEMBL29364307 0.69 TP53 (0.61) S100A4TSHRCYP3A4ALDH1A1TDP1
SCHEMBL440944 0.69 TP53 (0.61) S100A4TSHRCYP3A4ALDH1A1TDP1
SCHEMBL14907074 0.67 AHR (0.43) S100A4TSHRCYP3A4ALDH1A1ALOX15
SCHEMBL7799447 0.67

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118202023-A Polypropylene viscosity modifier and lubricating oil thereof 埃克森美孚化学专利公司 2024-06-14 CN disclosed
US-11926802-B2 Lubricating oil composition with viscosity modifier based on syndiotactic propylene-based ethylene- propylene copolymers with improved properties EXXONMOBIL CHEMICAL PATENTS INC. (US) 2024-03-12 US disclosed
US-20230242745-A1 Process for Production of Thermoplastic Vulcanizates using Supported Catalyst Systems and Compositions Made Therefrom EXXONMOBIL CHEMICAL PATENTS INC (US) 2023-08-03 US disclosed
US-20230174883-A1 LUBRICATING OIL COMPOSITION WITH VISCOSITY MODIFIER BASED ON SYNDIOTACTIC PROPYLENE-BASED ETHYLENE- PROPYLENE COPOLYMERS WITH IMPROVED PROPERTIES EXXONMOBIL CHEMICAL PATENTS INC. 2023-06-08 US disclosed
WO-2023081010-A1 POLYPROPYLENE VISCOSITY MODIFIERS AND LUBRICATING OILS THEREOF EXXONMOBIL CHEMICAL PATENTS INC. (US) 2023-05-11 WO disclosed
WO-2023081327-A1 LUBRICATING OIL COMPOSITION WITH VISCOSITY MODIFIER BASED ON SYNDIOTACTIC PROPYLENE-BASED ETHYLENE-PROPYLENE COPOLYMERS WITH IMPROVED PROPERTIES CHEVRON ORONITE COMPANY LLC (US) 2023-05-11 WO disclosed
US-20230148328-A1 SYNDIOTACTIC PROPYLENE-BASED ETHYLENE- PROPYLENE COPOLYMERS EXXONMOBIL CHEMICAL PATENTS INC (US) 2023-05-11 US disclosed
CN-106661488-B Syndiotactic propylene polymers and lubricating oils containing the same 埃克森美孚化学专利公司 2021-04-09 CN disclosed
US-10876063-B2 Syndiotactic propylene polymers and lubricating oils comprising the same EXXONMOBIL CHEMICAL PATENTS INC. (US) 2020-12-29 US disclosed
EP-3174961-B1 SYNDIOTACTIC PROPYLENE POLYMERS AND LUBRICATING OILS COMPRISING THE SAME EXXONMOBIL CHEMICAL PATENTS INC (US) 2019-11-20 EP disclosed
EP-3174961-A1 SYNDIOTACTIC PROPYLENE POLYMERS AND LUBRICATING OILS COMPRISING THE SAME ExxonMobil Chemical Patents Inc. (US) 2017-06-07 EP disclosed
US-20170130159-A1 Syndiotactic Propylene Polymers and Lubricating Oils Comprising the Same EXXONMOBIL CHEMICAL PATENTS INC. 2017-05-11 US disclosed
EP-2516598-B1 PROCESS FOR PRODUCING NOVEL SYNTHETIC BASESTOCKS EXXONMOBIL CHEM PATENTS INC (US) 2016-06-29 EP disclosed
WO-2016018523-A1 SYNDIOTACTIC PROPYLENE POLYMERS AND LUBRICATING OILS COMPRISING THE SAME EXXONMOBIL CHEMICAL PATENTS INC. (US) 2016-02-04 WO disclosed
US-20140213834-A1 ULTRA HIGH VISCOSITY SYNTHETIC BASE STOCKS AND PROCESSES FOR PREPARING SAME EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) 2014-07-31 US disclosed
US-8530712-B2 Process for producing novel synthetic basestocks EXXONMOBIL CHEMICAL PATENTS INC. (US) 2013-09-10 US disclosed
US-20130131410-A1 Process for Producing Novel Synthetic Basestocks EXXONMOBIL CHEMICAL PATENTS INC. (US) 2013-05-23 US disclosed
CN-101107260-B Transition metal complex, method for producing the same, substituted fluorene compound, method for producing the substituted fluorene compound, catalyst component for olefin polymerization, catalyst for olefin polymerization, and method for producing olefin polymer SUMITOMO CHEMICAL CO.,LTD. (JP) 2012-02-08 CN disclosed
US-20110160502-A1 Process for Producing Novel Synthetic Basestocks EXXONMOBIL CHEMICAL PATENTS INC. 2011-06-30 US disclosed
CN-101107260-A Transition metal complex, method for producing the same, substituted fluorene compound, method for producing the substituted fluorene compound, catalyst component for olefin polymerization, catalyst for olefin polymerization, and method for producing olefin polymer SUMITOMO CHEMICAL CO (JP) 2008-01-16 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130131410-A1 Process for Producing Novel Synthetic Basestocks PYM1, SCO2, SPIN4 S100A4 566/4885TSHR 4394/4885CYP3A4 3646/4885
US-20110160502-A1 Process for Producing Novel Synthetic Basestocks PYM1, SPIN4, SCO2 S100A4 651/4885TSHR 4354/4885CYP3A4 3997/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.