SCHEMBL2044633

SCHEMBL2044633

Clc1ccc2c(c1)[CH]c1cc(Cl)ccc1-2

nearest known ligand 0.52

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
S100A4 P26447 2/20 0.46
TP53 P04637 3/20 0.41
AHR P35869 2/20 0.41
PPOX P50336 1/20 0.41
CYP2A6 P11509 2/20 0.39
LMNA P02545 1/20 0.39
GPR3 P46089 1/20 0.38
TSHR P16473 5/20 0.38
CYP3A4 P08684 3/20 0.38
ALDH1A1 P00352 3/20 0.38
TDP1 Q9NUW8 2/20 0.38
ALOX15 P16050 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
CES1 P23141 1/20 0.37
PDK2 Q15119 1/20 0.37
HSD17B10 Q99714 2/20 0.36
HSD11B1 P28845 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2052786 0.77 S100A4 (0.46) S100A4TP53AHRPPOXCYP2A6
SCHEMBL28607196 0.71 S100A4 (0.68) S100A4TP53AHRPPOXCYP2A6
SCHEMBL715113 0.71 CYP2A6 (0.43) TP53CYP2A6LMNACYP3A4ALDH1A1
SCHEMBL11378149 0.70 AHR (0.61) TP53AHRLMNACYP3A4ALDH1A1
SCHEMBL464507 0.69 AHR (0.64) S100A4TP53AHRTSHRCYP3A4
SCHEMBL29624840 0.69 AHR (0.64) S100A4TP53AHRTSHRCYP3A4
SCHEMBL27502031 0.69 MAOA (0.37) TP53CYP2A6LMNACYP3A4ALDH1A1
SCHEMBL9092157 0.69 HSD11B1 (0.39) S100A4TP53AHRPPOXGPR3
SCHEMBL27845465 0.69 CYP2A6 (0.41) TP53CYP2A6LMNACYP3A4ALDH1A1
SCHEMBL27871372 0.69 CYP2A6 (0.41) TP53CYP2A6LMNACYP3A4ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5688735-A COORDINATION CATALYST FINA TECHNOLOGY, INC. (US) 1997-11-18 US claimed
EP-0577581-A2 Method for controlling the melting points and molecular weights of syndiotactic polyolefins using metallocene catalyst systems FINA TECHNOLOGY, INC. (US) 1994-01-05 EP claimed
CN-118202023-A Polypropylene viscosity modifier and lubricating oil thereof 埃克森美孚化学专利公司 2024-06-14 CN disclosed
US-11926802-B2 Lubricating oil composition with viscosity modifier based on syndiotactic propylene-based ethylene- propylene copolymers with improved properties EXXONMOBIL CHEMICAL PATENTS INC. (US) 2024-03-12 US disclosed
US-20230242745-A1 Process for Production of Thermoplastic Vulcanizates using Supported Catalyst Systems and Compositions Made Therefrom EXXONMOBIL CHEMICAL PATENTS INC (US) 2023-08-03 US disclosed
US-20230174883-A1 LUBRICATING OIL COMPOSITION WITH VISCOSITY MODIFIER BASED ON SYNDIOTACTIC PROPYLENE-BASED ETHYLENE- PROPYLENE COPOLYMERS WITH IMPROVED PROPERTIES EXXONMOBIL CHEMICAL PATENTS INC. 2023-06-08 US disclosed
US-20230148328-A1 SYNDIOTACTIC PROPYLENE-BASED ETHYLENE- PROPYLENE COPOLYMERS EXXONMOBIL CHEMICAL PATENTS INC (US) 2023-05-11 US disclosed
WO-2023081327-A1 LUBRICATING OIL COMPOSITION WITH VISCOSITY MODIFIER BASED ON SYNDIOTACTIC PROPYLENE-BASED ETHYLENE-PROPYLENE COPOLYMERS WITH IMPROVED PROPERTIES CHEVRON ORONITE COMPANY LLC (US) 2023-05-11 WO disclosed
WO-2023081010-A1 POLYPROPYLENE VISCOSITY MODIFIERS AND LUBRICATING OILS THEREOF EXXONMOBIL CHEMICAL PATENTS INC. (US) 2023-05-11 WO disclosed
WO-2023081325-A1 SYNDIOTACTIC PROPYLENE-BASED ETHYLENE-PROPYLENE COPOLYMERS EXXONMOBIL CHEMICAL PATENTS INC. (US) 2023-05-11 WO disclosed
CN-106661488-B Syndiotactic propylene polymers and lubricating oils containing the same 埃克森美孚化学专利公司 2021-04-09 CN disclosed
US-20170130159-A1 Syndiotactic Propylene Polymers and Lubricating Oils Comprising the Same EXXONMOBIL CHEMICAL PATENTS INC. 2017-05-11 US disclosed
EP-2516598-B1 PROCESS FOR PRODUCING NOVEL SYNTHETIC BASESTOCKS EXXONMOBIL CHEM PATENTS INC (US) 2016-06-29 EP disclosed
WO-2016018523-A1 SYNDIOTACTIC PROPYLENE POLYMERS AND LUBRICATING OILS COMPRISING THE SAME EXXONMOBIL CHEMICAL PATENTS INC. (US) 2016-02-04 WO disclosed
US-20140213834-A1 ULTRA HIGH VISCOSITY SYNTHETIC BASE STOCKS AND PROCESSES FOR PREPARING SAME EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) 2014-07-31 US disclosed
US-8530712-B2 Process for producing novel synthetic basestocks EXXONMOBIL CHEMICAL PATENTS INC. (US) 2013-09-10 US disclosed
US-20130131410-A1 Process for Producing Novel Synthetic Basestocks EXXONMOBIL CHEMICAL PATENTS INC. (US) 2013-05-23 US disclosed
CN-101107260-B Transition metal complex, method for producing the same, substituted fluorene compound, method for producing the substituted fluorene compound, catalyst component for olefin polymerization, catalyst for olefin polymerization, and method for producing olefin polymer SUMITOMO CHEMICAL CO.,LTD. (JP) 2012-02-08 CN disclosed
US-20110160502-A1 Process for Producing Novel Synthetic Basestocks EXXONMOBIL CHEMICAL PATENTS INC. 2011-06-30 US disclosed
CN-101107260-A Transition metal complex, method for producing the same, substituted fluorene compound, method for producing the substituted fluorene compound, catalyst component for olefin polymerization, catalyst for olefin polymerization, and method for producing olefin polymer SUMITOMO CHEMICAL CO (JP) 2008-01-16 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130131410-A1 Process for Producing Novel Synthetic Basestocks PYM1, SCO2, SPIN4 S100A4 566/4885TP53 4618/4885AHR 4116/4885
US-20110160502-A1 Process for Producing Novel Synthetic Basestocks PYM1, SPIN4, SCO2 S100A4 651/4885TP53 4639/4885AHR 4606/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.