SCHEMBL20528631

SCHEMBL20528631

Fc1ccc(-c2nc(S)n[nH]2)cc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.41
SMN1; SMN2 Q16637 2/20 0.41
NPC1 O15118 1/20 0.41
RAB9A P51151 1/20 0.41
ADORA3 P0DMS8 1/20 0.40
ADORA2A P29274 1/20 0.40
ALPL P05186 1/20 0.39
NR1H2 P55055 1/20 0.38
NR1H3 Q13133 1/20 0.38
DCUN1D1 Q96GG9 2/20 0.38
CYP1A2 P05177 2/20 0.38
NOTUM Q6P988 1/20 0.38
CYP2C19 P33261 1/20 0.38
ALDH1A1 P00352 2/20 0.38
PKM P14618 1/20 0.38
MAPK13 O15264 1/20 0.38
PRKD3 O94806 1/20 0.38
MAP4K4 O95819 1/20 0.38
FRK P42685 1/20 0.38
MAPK9 P45984 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11509840 0.80 MAPT (0.46) SMN1; SMN2NPC1RAB9AALPLNR1H2
SCHEMBL688527 0.79 NR1H2 (0.61) KDM4ESMN1; SMN2NPC1RAB9AADORA3
SCHEMBL15007066 0.78 NR1H2 (0.64) SMN1; SMN2NPC1RAB9AALPLNR1H2
SCHEMBL1032584 0.78 ROCK2 (0.45) KDM4ESMN1; SMN2MAP4K4CLK4
SCHEMBL8808 0.76 ALPL (0.67) KDM4ESMN1; SMN2NPC1RAB9AALPL
SCHEMBL421548 0.76 HTT (0.52) KDM4ESMN1; SMN2NPC1RAB9AALPL
SCHEMBL11512806 0.76 KDM4E (0.65) KDM4ESMN1; SMN2NPC1RAB9AADORA3
SCHEMBL11686492 0.73 ENPP2 (0.41) KDM4ESMN1; SMN2ADORA3ADORA2AALPL
SCHEMBL11510943 0.72 ALDH1A1 (0.41) KDM4ESMN1; SMN2NPC1RAB9ANR1H2
SCHEMBL29035844 0.72 NR1H2 (0.79) KDM4ESMN1; SMN2NPC1RAB9AADORA2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108689951-B Triazole compound and application thereof in agriculture 东莞市东阳光农药研发有限公司 2020-05-19 CN disclosed
EP-3606910-A1 TRIAZOLE COMPOUND AND USE THEREOF IN AGRICULTURE Dongguan Hec Pesticides R&D Co., Ltd. (CN) 2020-02-12 EP disclosed
WO-2018184579-A1 TRIAZOLE COMPOUND AND USE THEREOF IN AGRICULTURE DONGGUAN HEC TECH R&D CO., LTD. (CN) 2018-10-11 WO disclosed