Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.33 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.32 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30545299 | 1.00 | ACHE (0.34) | ACHECYP11B2CYP11B1PTGS2MAOA | |
| SCHEMBL1453931 | 0.80 | ACHE (0.32) | ACHECYP11B2CYP11B1PTGS2 | |
| SCHEMBL7937192 | 0.79 | PTGS2 (0.39) | ACHECYP11B2CYP11B1PTGS2MAOA | |
| SCHEMBL2743954 | 0.75 | CYP11B2 (0.41) | ACHECYP11B2CYP11B1PTGS2MAOA | |
| SCHEMBL15121440 | 0.75 | CYP11B2 (0.41) | ACHECYP11B2CYP11B1PTGS2MAOA | |
| SCHEMBL1452101 | 0.75 | ACHE (0.41) | ACHECYP11B2CYP11B1PTGS2MAOA | |
| SCHEMBL8417236 | 0.75 | ACHE (0.33) | ACHECYP11B2CYP11B1PTGS2 | |
| SCHEMBL29262860 | 0.75 | CYP11B1 (0.38) | ACHECYP11B2CYP11B1PTGS2MAOA | |
| SCHEMBL8854215 | 0.73 | ACHE (0.40) | ACHECYP11B2CYP11B1PTGS2MAOA | |
| Hydrochloric Acid SCHEMBL29262838 | 0.73 | CYP11B2 (0.39) | CYP11B2CYP11B1MAOAMAOBCYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3606931-B1 | DIHYDROCARBYL-SILYL-BRIDGED-SUBSTITUTED CYCLOPENTADIENYL METALLOCENE COMPLEXES FOR OLEFIN POLYMERIZATION | SABIC GLOBAL TECHNOLOGIES BV (NL) | 2025-08-27 | — | — | EP | disclosed |
| US-11352386-B2 | Dihydrocarbyl-silyl-bridged-substituted cyclopentadienyl metallocene complexes for olefin polymerization | SABIC GLOBAL TECHNOLOGIES B.V. (NL) | 2022-06-07 | — | — | US | disclosed |
| US-20200199165-A1 | DIHYDROCARBYL-SILYL-BRIDGED-SUBSTITUTED CYCLOPENTADIENYL METALLOCENE COMPLEXES FOR OLEFIN POLYMERIZATION | SABIC GLOBAL TECHNOLOGIES B.V. (NL) | 2020-06-25 | — | — | US | disclosed |
| EP-3606931-A1 | DIHYDROCARBYL-SILYL-BRIDGED-SUBSTITUTED CYCLOPENTADIENYL METALLOCENE COMPLEXES FOR OLEFIN POLYMERIZATION | SABIC Global Technologies B.V. (NL) | 2020-02-12 | — | — | EP | disclosed |
| WO-2018185176-A1 | DIHYDROCARBYL-SILYL-BRIDGED-SUBSTITUTED CYCLOPENTADIENYL METALLOCENE COMPLEXES FOR OLEFIN POLYMERIZATION | SABIC GLOBAL TECHNOLOGIES B.V. (NL) | 2018-10-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11352386-B2 | Dihydrocarbyl-silyl-bridged-substituted cyclopentadienyl metallocene complexes for olefin polymerization | C9, APOL1, ACSL3 | ACHE 4043/4885CYP11B2 1938/4885CYP11B1 1268/4885 |
| US-20200199165-A1 | DIHYDROCARBYL-SILYL-BRIDGED-SUBSTITUTED CYCLOPENTADIENYL METALLOCENE COMPLEXES FOR OLEFIN POLYMERIZATION | APOL1, ACSL3, OXA1L | ACHE 4128/4885CYP11B2 2228/4885CYP11B1 1436/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.