Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8900515 | 0.75 | AGTR1 (0.36) | AGTR1AGTR2 | |
| SCHEMBL16403650 | 0.72 | LTB4R2 (0.35) | AGTR1AGTR2 | |
| SCHEMBL9667305 | 0.71 | AGTR1 (0.46) | AGTR1AGTR2 | |
| SCHEMBL594508 | 0.71 | AGTR1 (0.52) | AGTR1AGTR2 | |
| Carboxylic Acid Metabolite SCHEMBL179 | 0.71 | AGTR2 (0.72) | AGTR1AGTR2 | |
| SCHEMBL3118878 | 0.71 | AGTR1 (0.56) | AGTR1AGTR2 | |
| SCHEMBL6953051 | 0.71 | HSD11B1 (0.47) | AGTR1AGTR2 | |
| SCHEMBL7311684 | 0.70 | AGTR1 (0.58) | AGTR1AGTR2 | |
| SCHEMBL7308377 | 0.70 | AGTR1 (0.61) | AGTR1AGTR2 | |
| Carboxylic Acid Metabolite SCHEMBL9468825 | 0.70 | AGTR2 (0.71) | AGTR1AGTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110160120-A1 | Agonists of Guanylate Cyclase Useful for the Treatment of Gastrointestinal Disorders, Inflammation, Cancer and Other Disorders | SYNERGY PHARMACEUTICALS INC. (US) | 2011-06-30 | — | — | US | disclosed |