Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 4/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | CNR1 | P21554 | 5/20 | 0.39 |
| ▸ | CNR2 | P34972 | 5/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 8/20 | 0.38 |
| ▸ | PDE4D | Q08499 | 4/20 | 0.38 |
| ▸ | MET | P08581 | 1/20 | 0.37 |
| ▸ | DRD4 | P21917 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20530369 | 0.91 | MET (0.44) | HPGDGAANPSR1CNR1CNR2 | |
| SCHEMBL20530335 | 0.90 | MET (0.47) | MEN1KMT2AMET | |
| SCHEMBL20530346 | 0.88 | POLB (0.38) | HPGDMEN1KMT2ATSHRPDE4B | |
| SCHEMBL20530311 | 0.88 | GPR119 (0.40) | MEN1KMT2APDE4BMET | |
| SCHEMBL20530319 | 0.88 | MET (0.43) | HPGDMEN1KMT2ATSHRALDH1A1 | |
| SCHEMBL20530322 | 0.88 | MET (0.43) | HPGDMEN1KMT2ATSHRALDH1A1 | |
| SCHEMBL20530296 | 0.87 | CNR1 (0.43) | HPGDMEN1KMT2ATSHRALDH1A1 | |
| SCHEMBL20530328 | 0.87 | MKNK2 (0.39) | MEN1KMT2AMET | |
| SCHEMBL1330786 | 0.86 | MET (0.51) | MET | |
| SCHEMBL22729926 | 0.85 | MET (0.36) | HPGDGAANPSR1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2571878-B1 | NOVEL 3,5-DISUBSTITUED-3H-IMIDAZO[4,5-B]PYRIDINE AND 3,5- DISUBSTITUED -3H-[1,2,3]TRIAZOLO[4,5-B]PYRIDINE COMPOUNDS AS MODULATORS OF PROTEIN KINASES | INCOZEN THERAPEUTICS PVT LTD (IN) | 2018-10-17 | — | — | EP | claimed |