Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | MET | P08581 | 1/20 | 0.38 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.38 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.38 |
| ▸ | P2RX7 | Q99572 | 4/20 | 0.37 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.37 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.36 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.36 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20530311 | 0.94 | GPR119 (0.40) | METADORA2AADORA1P2RX7PDE4B | |
| SCHEMBL20530357 | 0.91 | MEN1 (0.42) | METADORA2AADORA1PDE4BPDE4D | |
| SCHEMBL20530335 | 0.90 | MET (0.47) | METADORA2AADORA1MEN1KMT2A | |
| SCHEMBL20530288 | 0.88 | HPGD (0.46) | METPDE4BPDE4DMEN1KMT2A | |
| SCHEMBL1331840 | 0.87 | MET (0.50) | MET | |
| SCHEMBL20530325 | 0.86 | MEN1 (0.41) | METADORA2AADORA1MEN1NPC1 | |
| SCHEMBL20530328 | 0.86 | MKNK2 (0.39) | METADORA2AADORA1MEN1KMT2A | |
| SCHEMBL22729926 | 0.85 | MET (0.36) | METADORA2AADORA1MEN1KMT2A | |
| SCHEMBL22729947 | 0.84 | MET (0.36) | POLBMETADORA2AADORA1MEN1 | |
| SCHEMBL22729945 | 0.84 | MET (0.36) | METADORA2AADORA1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2571878-B1 | NOVEL 3,5-DISUBSTITUED-3H-IMIDAZO[4,5-B]PYRIDINE AND 3,5- DISUBSTITUED -3H-[1,2,3]TRIAZOLO[4,5-B]PYRIDINE COMPOUNDS AS MODULATORS OF PROTEIN KINASES | INCOZEN THERAPEUTICS PVT LTD (IN) | 2018-10-17 | — | — | EP | claimed |