Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.41 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | TET3 | O43151 | 1/20 | 0.38 |
| ▸ | TET2 | Q6N021 | 1/20 | 0.38 |
| ▸ | TET1 | Q8NFU7 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.38 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.38 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.38 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.38 |
| ▸ | ATR | Q13535 | 1/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.38 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.38 |
| ▸ | FYN | P06241 | 4/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20530324 | 0.90 | L3MBTL1 (0.52) | MAP4K4KDM4EALDH1A1MAPTTET3 | |
| SCHEMBL20530297 | 0.90 | MKNK1 (0.46) | MAP4K4KDM4ETET3TET2TET1 | |
| SCHEMBL20530341 | 0.88 | HDAC6 (0.43) | HDAC6MAP4K4KDM4EALDH1A1MAPT | |
| SCHEMBL20530293 | 0.88 | TP53 (0.48) | MAP4K4MAPTATRMEN1KMT2A | |
| SCHEMBL22729929 | 0.87 | HDAC6 (0.39) | HDAC6KDM4EALDH1A1MAPTL3MBTL1 | |
| SCHEMBL20530355 | 0.86 | RIPK1 (0.43) | HDAC6KDM4EALDH1A1MAPTMKNK1 | |
| SCHEMBL20530354 | 0.85 | AR (0.39) | HDAC6MAP4K4KDM4EALDH1A1MAPT | |
| SCHEMBL1330112 | 0.84 | MET (0.53) | — | |
| SCHEMBL20530339 | 0.84 | ATR (0.41) | HDAC6MKNK1MKNK2ATR | |
| SCHEMBL20530329 | 0.83 | MKNK1 (0.40) | HDAC6ALDH1A1MKNK1MKNK2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2571878-B1 | NOVEL 3,5-DISUBSTITUED-3H-IMIDAZO[4,5-B]PYRIDINE AND 3,5- DISUBSTITUED -3H-[1,2,3]TRIAZOLO[4,5-B]PYRIDINE COMPOUNDS AS MODULATORS OF PROTEIN KINASES | INCOZEN THERAPEUTICS PVT LTD (IN) | 2018-10-17 | — | — | EP | claimed |