SCHEMBL20530587

SCHEMBL20530587

C#CCOc1cccc2cccc(O)c12

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOB P27338 3/20 0.42
TXNRD1 Q16881 1/20 0.41
TXNRD3 Q86VQ6 1/20 0.41
TXNRD2 Q9NNW7 1/20 0.41
CYP1A1 P04798 1/20 0.41
CYP1A2 P05177 1/20 0.41
CYP2B6 P20813 1/20 0.41
CYP3A4 P08684 1/20 0.41
CYP2A6 P11509 1/20 0.41
MAPT P10636 2/20 0.40
MEN1 O00255 1/20 0.37
ALDH1A1 P00352 1/20 0.37
DNMT1 P26358 1/20 0.37
CACNA1B Q00975 1/20 0.37
APBA1 Q02410 1/20 0.37
KMT2A Q03164 1/20 0.37
MCL1 Q07820 1/20 0.37
APOBEC3G Q9HC16 1/20 0.37
HPGD P15428 2/20 0.37
LMNA P02545 2/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5669332 0.80 MAPT (0.57) MAOBCYP3A4CYP2A6MAPTALDH1A1
SCHEMBL20530567 0.79 MAOB (0.49) MAOBTXNRD1TXNRD3TXNRD2CYP3A4
SCHEMBL18470241 0.78 CA2 (0.46) MAOBTXNRD1TXNRD3TXNRD2CYP3A4
SCHEMBL20530571 0.77 CYP3A4 (0.49) MAOBCYP3A4CYP2A6MAPTMEN1
SCHEMBL11883080 0.77 MEN1 (0.48) CYP3A4MAPTMEN1ALDH1A1DNMT1
SCHEMBL18335399 0.76 CYP3A4 (0.41) MAOBCYP1A1CYP1A2CYP2B6CYP3A4
SCHEMBL20530584 0.74 MAOB (0.46) MAOBCYP1A1CYP1A2MAPTHPGD
SCHEMBL2204213 0.73 HTR1B (0.55) MAOBCYP1A2CYP3A4CYP2A6MEN1
SCHEMBL30000708 0.73 HTR1B (0.55) MAOBCYP1A2CYP3A4CYP2A6MEN1
SCHEMBL10347560 0.72 MAPT (0.56) MAOBCYP3A4CYP2A6MAPTHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11117873-B2 Oxazine compound, composition, and cured product DIC CORPORATION (JP) 2021-09-14 US disclosed
US-11117872-B2 Oxazine compound, composition and cured product DIC CORPORATION (JP) 2021-09-14 US disclosed
US-11028059-B2 Oxazine compound, composition and cured product DIC CORPORATION (JP) 2021-06-08 US disclosed
CN-108368217-B Oxazine compound, composition and cured product DIC株式会社 2021-05-07 CN disclosed
CN-108368218-B Oxazine compound, composition and cured product DIC株式会社 2020-11-06 CN disclosed
CN-108368216-B Oxazine compound, composition and cured product DIC株式会社 2020-09-18 CN disclosed
US-20180362480-A1 OXAZINE COMPOUND, COMPOSITION, AND CURED PRODUCT DIC CORPORATION (JP) 2018-12-20 US disclosed
US-20180362478-A1 OXAZINE COMPOUND, COMPOSITION AND CURED PRODUCT DIC CORPORATION (JP) 2018-12-20 US disclosed
US-20180362477-A1 OXAZINE COMPOUND, COMPOSITION AND CURED PRODUCT DIC CORPORATION (JP) 2018-12-20 US disclosed
EP-3388461-A1 OXAZINE COMPOUND, COMPOSITION, AND CURED PRODUCT DIC Corporation (JP) 2018-10-17 EP disclosed
EP-3388460-A1 OXAZINE COMPOUND, COMPOSITION AND CURED PRODUCT DIC Corporation (JP) 2018-10-17 EP disclosed
EP-3388459-A1 OXAZINE COMPOUND, COMPOSITION AND CURED PRODUCT DIC Corporation (JP) 2018-10-17 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11028059-B2 Oxazine compound, composition and cured product KDM5A, WDR5, RNF5 MAOB 1747/4885TXNRD1 3520/4885TXNRD3 3848/4885
US-20180362480-A1 OXAZINE COMPOUND, COMPOSITION, AND CURED PRODUCT KDM5A, WDR5, SMC4 MAOB 1509/4885TXNRD1 3327/4885TXNRD3 3699/4885
US-20180362478-A1 OXAZINE COMPOUND, COMPOSITION AND CURED PRODUCT KDM5A, WDR5, RNF5 MAOB 1731/4885TXNRD1 3492/4885TXNRD3 3827/4885
US-11117873-B2 Oxazine compound, composition, and cured product KDM5A, WDR5, SMC4 MAOB 1509/4885TXNRD1 3327/4885TXNRD3 3699/4885
US-11117872-B2 Oxazine compound, composition and cured product KDM5A, WDR5, RNF5 MAOB 1731/4885TXNRD1 3492/4885TXNRD3 3827/4885
US-20180362477-A1 OXAZINE COMPOUND, COMPOSITION AND CURED PRODUCT KDM5A, WDR5, RNF5 MAOB 1747/4885TXNRD1 3520/4885TXNRD3 3848/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.