Known targets — ChEMBL curated mechanism
PPARDPTGS1PTGS2dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Lysine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSR | P00390 | 1/20 | 0.67 |
| ▸ | ARG2 | P78540 | 4/20 | 0.43 |
| ▸ | ARG1 | P05089 | 3/20 | 0.43 |
| ▸ | NOS2 | P35228 | 5/20 | 0.42 |
| ▸ | NOS1 | P29475 | 4/20 | 0.42 |
| ▸ | NOS3 | P29474 | 3/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Lysine SCHEMBL7113294 | 1.00 | GSR (0.67) | GSRARG2ARG1NOS2NOS1 | |
| Lysine SCHEMBL7113285 | 1.00 | GSR (0.67) | GSRARG2ARG1NOS2NOS1 | |
| Lysine SCHEMBL28275584 | 0.98 | GSR (0.65) | GSRARG2ARG1NOS2NOS1 | |
| Lysine SCHEMBL3312731 | 0.97 | GSR (0.62) | GSRARG2ARG1NOS2NOS1 | |
| Lysine SCHEMBL3312740 | 0.97 | GSR (0.62) | GSRARG2ARG1NOS2NOS1 | |
| Ornithine Aketoglutarate SCHEMBL29232510 | 0.95 | GSR (0.58) | GSRARG2ARG1NOS2NOS1 | |
| Lysine SCHEMBL28189328 | 0.93 | GSR (0.57) | GSRARG2ARG1NOS2NOS1 | |
| Lysine SCHEMBL28189329 | 0.93 | GSR (0.57) | GSRARG2ARG1NOS2NOS1 | |
| Lysine SCHEMBL29066022 | 0.91 | GSR (0.56) | GSRARG2ARG1NOS2NOS1 | |
| Lysine SCHEMBL28688782 | 0.89 | GSR (0.61) | GSRARG2ARG1NOS2NOS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3386697-A1 | PROCESS FOR PARTIAL DELIGNIFICATION AND FILLING OF A LIGNOCELLULOSIC MATERIAL, AND COMPOSITE STRUCTURE ABLE TO BE OBTAINED BY THIS PROCESS | Boitouzet, Timothée (FR) | 2018-10-17 | — | — | EP | disclosed |