Lysine

Lysine

SCHEMBL7113285

C[N+](C)(C)CCO.NCCCCC(N)C(=O)O

nearest known ligand 0.67

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

PPARDPTGS1PTGS2dacAdacBdacCftsImrcAmrcBmrdA

The experimentally established mechanism targets of Lysine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
▸ GSR P00390 1/20 0.67
▸ ARG2 P78540 4/20 0.43
▸ ARG1 P05089 3/20 0.43
▸ NOS2 P35228 5/20 0.42
▸ NOS1 P29475 4/20 0.42
▸ NOS3 P29474 3/20 0.42
▸ CYP1A2 P05177 1/20 0.42
▸ CYP3A4 P08684 1/20 0.42
▸ TSHR P16473 1/20 0.42
▸ RNPEP Q9H4A4 1/20 0.42
▸ BLM P54132 1/20 0.41
▸ MEN1 O00255 2/20 0.40
▸ KMT2A Q03164 2/20 0.40
▸ CYP2C19 P33261 1/20 0.40
▸ LMNA P02545 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Lysine SCHEMBL7113294 1.00 GSR (0.67) GSRARG2ARG1NOS2NOS1
Lysine SCHEMBL20530995 1.00 GSR (0.67) GSRARG2ARG1NOS2NOS1
Lysine SCHEMBL28275584 0.98 GSR (0.65) GSRARG2ARG1NOS2NOS1
Lysine SCHEMBL3312731 0.97 GSR (0.62) GSRARG2ARG1NOS2NOS1
Lysine SCHEMBL3312740 0.97 GSR (0.62) GSRARG2ARG1NOS2NOS1
Ornithine Aketoglutarate SCHEMBL29232510 0.95 GSR (0.58) GSRARG2ARG1NOS2NOS1
Lysine SCHEMBL28189328 0.93 GSR (0.57) GSRARG2ARG1NOS2NOS1
Lysine SCHEMBL28189329 0.93 GSR (0.57) GSRARG2ARG1NOS2NOS1
Lysine SCHEMBL29066022 0.91 GSR (0.56) GSRARG2ARG1NOS2NOS1
Lysine SCHEMBL28688782 0.89 GSR (0.61) GSRARG2ARG1NOS2NOS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 57 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114621984-A Method for synthesizing 1, 5-pentanediamine by strengthening lysine decarboxylase through ionic liquid 中国科学院过程工程研究所 2022-06-14 — — CN claimed
CN-114426992-A Amino functionalized ionic liquid reinforced CO2Biotransformation process 中国科学院过程工程研究所 2022-05-03 — — CN claimed
CN-112358627-B Method for promoting starch dissolution by ionic liquid, sol system and application 华南理工大学 2021-08-10 — — CN claimed
CN-112646613-A Absorbent and method for separating and recovering carbon dioxide in blast furnace gas 中石化南京化工研究院有限公司 2021-04-13 — — CN claimed
CN-112358627-A Method for promoting starch dissolution by ionic liquid, sol system and application 华南理工大学 2021-02-12 — — CN claimed
CN-108794652-B Chitin integrated production system and processing method thereof 中国科学院过程工程研究所 2021-02-05 — — CN claimed
CN-108786479-B Cation exchange membrane, preparation thereof and application thereof in separation of alkane/olefin 河南科技大学 2020-04-28 — — CN claimed
CN-108786479-A It a kind of cation-exchange membrane and its prepares and the application in detaching alkane/olefin 河南科技大学 2018-11-13 — — CN claimed
CN-108794652-A A kind of chitin integraterd manufacturing system and its processing method 中国科学院过程工程研究所 2018-11-13 — — CN claimed
CN-108138080-A Free fatty is removed from glyceride oil 英国贝尔法斯特女王大学 2018-06-08 — — CN claimed
CN-107312109-A Chitin separating and extracting process in a kind of shrimp and crab shells based on degradable ionic liquid 中国科学院过程工程研究所 2017-11-03 — — CN claimed
CN-105916969-A Removal of free fatty acids from glyceride oils 贝尔法斯特女王大学 2016-08-31 — — CN claimed
CN-104437008-A Method for preparing biological methane by purifying and purifying biogas NANJING UNIVERSITY OF TECHNOLOGY 2015-03-25 — — CN claimed
CN-122032506-A Carbon trapping material and preparation method and application thereof 中国科学院苏州纳米技术与纳米仿生研究所 2026-05-15 — — CN disclosed
CN-120441873-A High amylose starch-fatty acid compound and preparation method thereof 华南理工大学 2025-08-08 — — CN disclosed
CN-114621984-B Method for synthesizing 1, 5-pentanediamine by using ionic liquid to strengthen lysine decarboxylase 中国科学院过程工程研究所 2025-01-28 — — CN disclosed
CN-104437008-A Method for preparing biological methane by purifying and purifying biogas NANJING UNIVERSITY OF TECHNOLOGY 2015-03-25 — — CN disclosed
WO-2013033046-A2 FLUORESCENT PL MARKERS FOR ISOELECTRIC FOCUSING SEPARATIONS AND FLUORESCENT LABELING VIGH GYULA (US) 2013-03-07 — — WO disclosed
EP-1351566-A2 COMPUTER SYSTEM FOR DETERMINING A CUSTOMIZED ANIMAL FEED CAN TECHNOLOGIES, INC. (US) 2003-10-15 — — EP disclosed
WO-2002047473-A2 COMPUTER SYSTEM FOR DETERMINING A CUSTOMIZED ANIMAL FEED CAN TECHNOLOGIES, INC. (US) 2002-06-20 — — WO disclosed
Send feedback