Known targets — ChEMBL curated mechanism
PPARDPTGS1PTGS2dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Lysine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSR | P00390 | 1/20 | 0.62 |
| ▸ | ARG2 | P78540 | 4/20 | 0.44 |
| ▸ | NOS2 | P35228 | 5/20 | 0.43 |
| ▸ | NOS1 | P29475 | 4/20 | 0.43 |
| ▸ | BLM | P54132 | 1/20 | 0.43 |
| ▸ | ARG1 | P05089 | 3/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | SLC5A7 | Q9GZV3 | 1/20 | 0.41 |
| ▸ | NOS3 | P29474 | 3/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Lysine SCHEMBL3312731 | 1.00 | GSR (0.62) | GSRARG2NOS2NOS1BLM | |
| Lysine SCHEMBL28275584 | 0.98 | GSR (0.65) | GSRARG2NOS2NOS1BLM | |
| Lysine SCHEMBL7113294 | 0.97 | GSR (0.67) | GSRARG2NOS2NOS1BLM | |
| Lysine SCHEMBL20530995 | 0.97 | GSR (0.67) | GSRARG2NOS2NOS1BLM | |
| Lysine SCHEMBL7113285 | 0.97 | GSR (0.67) | GSRARG2NOS2NOS1BLM | |
| Lysine SCHEMBL28189328 | 0.93 | GSR (0.57) | GSRARG2NOS2NOS1BLM | |
| Lysine SCHEMBL28189329 | 0.93 | GSR (0.57) | GSRARG2NOS2NOS1BLM | |
| Ornithine Aketoglutarate SCHEMBL29232510 | 0.92 | GSR (0.58) | GSRARG2NOS2NOS1BLM | |
| Lysine SCHEMBL29066022 | 0.91 | GSR (0.56) | GSRARG2NOS2NOS1BLM | |
| Lysine SCHEMBL28084777 | 0.89 | GSR (0.53) | GSRARG2NOS2NOS1BLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9717693-B2 | Compositions of microparticles and granules for oral controlled release of substances for veterinary use | KEMIN INDUSTRIES, INC. (US) | 2017-08-01 | — | — | US | disclosed |
| US-20100112075-A1 | COMPOSITIONS OF MICROPARTICLES AND GRANULES FOR ORAL CONTROLLED RELEASE OF SUBSTANCES FOR VETERINARY USE | EURHEMA S.R.I. (IT) | 2010-05-06 | — | — | US | disclosed |