Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGFR | P43088 | 3/20 | 0.42 |
| ▸ | CTSA | P10619 | 4/20 | 0.36 |
| ▸ | RIPK1 | Q13546 | 3/20 | 0.35 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.34 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.33 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.33 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL21632094 | 0.82 | PTGFR (0.45) | PTGFRCTSAFFAR4FFAR1 | |
| SCHEMBL21632086 | 0.82 | PTGFR (0.39) | PTGFRCTSAFFAR4NR3C2FFAR1 | |
| SCHEMBL9885325 | 0.75 | PTGS2 (0.39) | PTGFR | |
| SCHEMBL5776235 | 0.72 | NR3C1 (0.42) | NR3C2 | |
| SCHEMBL21656599 | 0.72 | MTNR1A (0.38) | PTGFRSTING1 | |
| SCHEMBL17006206 | 0.71 | HSD17B10 (0.46) | CTSAFFAR4 | |
| SCHEMBL21656334 | 0.71 | MTNR1A (0.38) | PTGFRNR3C2STING1 | |
| SCHEMBL10709397 | 0.70 | HTR7 (0.30) | — | |
| SCHEMBL379397 | 0.70 | NR3C1 (0.47) | FFAR4NR3C2FFAR1 | |
| SCHEMBL10254200 | 0.69 | HPGD (0.36) | RIPK1NR3C2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3609869-A1 | SUBSTITUTED N-ARYLETHYL-2-ARYLQUINOLINE-4-CARBOXAMIDES AND USE THEREOF | Bayer Aktiengesellschaft (DE) | 2020-02-19 | — | — | EP | disclosed |
| WO-2018189011-A1 | SUBSTITUTED N-ARYLETHYL-2-ARYLQUINOLINE-4-CARBOXAMIDES AND USE THEREOF | BAYER AKTIENGESELLSCHAFT (DE) | 2018-10-18 | — | — | WO | disclosed |