Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 4/20 | 0.38 |
| ▸ | MTNR1B | P49286 | 4/20 | 0.38 |
| ▸ | PTGFR | P43088 | 3/20 | 0.36 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL21632094 | 0.85 | PTGFR (0.45) | PTGFR | |
| SCHEMBL21656201 | 0.80 | NR3C1 (0.41) | MTNR1AMTNR1B | |
| Hydrochloric Acid SCHEMBL21708639 | 0.80 | PTGFR (0.33) | PTGFR | |
| SCHEMBL21656334 | 0.79 | MTNR1A (0.38) | MTNR1AMTNR1BPTGFRSTING1 | |
| SCHEMBL21656602 | 0.78 | MTNR1A (0.41) | MTNR1AMTNR1BPTGFRSTING1 | |
| SCHEMBL21656595 | 0.76 | KCNN4 (0.39) | MTNR1AMTNR1B | |
| SCHEMBL20534675 | 0.72 | PTGFR (0.42) | PTGFRSTING1 | |
| SCHEMBL21656321 | 0.71 | MEN1 (0.42) | MTNR1AMTNR1BSTING1 | |
| SCHEMBL21656118 | 0.71 | MTNR1A (0.41) | MTNR1AMTNR1BPTGFRSTING1 | |
| SCHEMBL9885325 | 0.68 | PTGS2 (0.39) | PTGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11136296-B2 | Substituted N-arylethyl-2-arylquinoline-4-carboxamides and use thereof | BAYER AKTIENGESELLSCHAFT (DE) | 2021-10-05 | — | — | US | disclosed |
| US-20200031775-A1 | SUBSTITUTED N-ARYLETHYL-2-ARYLQUINOLINE-4-CARBOXAMIDES AND USE THEREOF | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2020-01-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200031775-A1 | SUBSTITUTED N-ARYLETHYL-2-ARYLQUINOLINE-4-CARBOXAMIDES AND USE THEREOF | AADAC, NAT1, EPX | MTNR1A 367/4885MTNR1B 289/4885PTGFR 1050/4885 |
| US-11136296-B2 | Substituted N-arylethyl-2-arylquinoline-4-carboxamides and use thereof | AADAC, NAT1, EPX | MTNR1A 367/4885MTNR1B 289/4885PTGFR 1050/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.